【正文】 陽性 11(42%) 3(6%) 14 陰性 15(58% 43(94%) 58 BALGM 陽性 23(88%) 6(13%) 29 陰性 3 (12%) 40(87%) 43 BAL鏡檢和培養(yǎng) 陽性 15(57%) 14(30%) 29 陰性 11(43%) 32(70%) 43 American Journal of Respiratory and Critical Care Medicine Vol 177. pp. 2734, (2023) GM可系統(tǒng)性評價抗真菌治療效果 姚佳峰 ,蘇東 ,黃勇等 .血清半乳甘露聚糖試驗對侵襲性曲霉菌感染早期診斷和治療的價值 .中華血液學雜志 2023年 9月第 30卷第 9期 592595 侵襲性真菌感染中葡聚糖 (glucan)檢測 AML, MDS Receiving antifungal prophylaxis Clin Infect Dis 2023。10:R32 呼吸道分泌物檢測結(jié)果 有助于 IFI早期診斷 Perfect JR, Cox GM, Lee JY,.et al. The impact of culture isolation of Aspergillus species: a hospitalbased survey of aspergillosis. Clin Infectious 。19(1):2539 94% 61% 30% 27% 20% 10% 早期 CT檢查有助于提供 IPA治療滿意率 R. E. Greene, H. T. Schlamm, P. Stark, et al. Radiologic findings in acute invasive pulmonary aspergillosis: Utility and reliability of halo sign and aircrescent sign for diagnosis and treatment of IPA in highrisk patients. Presented at 13th ECCMID,1013 May 2023, Glasgow, UK 肺曲菌病暈輪征 Halo sign 肺曲菌病 新月征 (aircrescent sign) 確診和臨床診斷病人暈輪征 分類 病人總數(shù) CT檢查例數(shù) 陽性例數(shù) 陽性率 血液腫瘤病人 38 35 28 80% 其他病人 67 17 3 17% 83例非血液病患者 IPA的 CT表現(xiàn) 影像學改變 例數(shù)（ %） 正常 0 彌漫性網(wǎng)狀小結(jié)節(jié)影 12（ 14%） 非特異滲出和實變 42（ 50%） 結(jié)節(jié)樣改變 25（ 30%） 新月征 1（ 1%） 暈論征 2（ 2%） 空洞形成 1（ 1%） Crit Care. 2023。 20230604 20231017 20231017 Transverse CT scan in 46yearold woman shows several nodules in the lung bases (7mmthick section). Most of the nodules have smooth margins. Transverse CT scan in 47yearold man demonstrates multiple illdefined irregularly marginated nodules in the upper lobes (arrows) (5mmthick section). Transverse CT scan in 51yearold woman (7mmthick section). (a) Scan obtained at level of the bronchus of the upper lobe in the right lung shows several nodules (thin arrows), one of which is cavitated (thick arrow). (b) Scan shows cavitated mass in the apex in the right lung (arrow). Solid and cavitated nodules are seen in the apex in the left lung. Contrastenhanced transverse CT scan in 55yearold man (5mmthick section). (a) Scan shows lowattenuating mass or lymphadenopathy in the hilum in the left lung (white arrow). The mass had an endoluminal ponent (black arrow), which protruded into the bronchus of the upper lobe in the left lung. (b) Scan shows postobstructive consolidation (arrow) of the lingula distal to the mass. Patterns and Distribution of Pulmonary Abnormalities of Initial CT Scans Patten Patients, No. (%) Bilateral Unilateral Pulmonary nodules/masses 21(%) 14 7 Airspace consolidation 17(%) 11 6 Reticular pattern 1(%) 1 0 Groundglass attenuation 5( %) 4 1 CHEST February 2023 vol. 129 no. 2 333340 Immunopromised patients often undergo an evoluti