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炎癥性腸病ppt課件-文庫吧資料

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【正文】 l Section Time bar Video Controls Comment SMALL INTESTINE IMAGING IN 3 EASY STEPS 檢查 三步驟 1. Ingesting the capsule( 吞膠囊) 2. Undergoing the procedure ( 數(shù)據(jù)記錄) 3. Viewing the results ( 讀結(jié)果) Angiodysplasia SB Tumor Crohn’s disease Celiac Sprue 雙氣囊全小腸鏡 C22A 男 18歲,反復(fù)腹痛伴發(fā)熱 1年余 小腸 Crohn’s 病 Evolution of IBD therapy: the result of understanding IBD pathogenesis 1940’s Sulfasalazine 1950’s Cortisone, ACTH 1960’s Azathioprine 1970’s 5ASA 1980’s 6MP, metronidazole, elemental diets 1990’s (early) Cyclosporine, budenoside, methotrexate, antibiotics 1990’s (late) Biologicals, probiotics, leukapheresis 2022’s Combination therapies 炎癥性腸病的治療 生物治療 1020% 2040% 5070% 免疫抑制劑 治療 傳統(tǒng)治療 : 皮質(zhì)激素 5ASA Chronic gut inflammation: imbalance of immune mediators TNFa IL1b IL8 IL12 IFNg TGFb IL10 IL1ra IL4/13 TNFa IL1b IL8 IL12 IFNg TGFb IL10 IL1ra IL4/13 Rebinant cytokinebased therapy for IBD Proinflammatory Antiinflammatory Proinflammatory Antiinflammatory Anticytokine antibodybased therapy for IBD TNFa IL1b IL8 IL12 IFNg TGFb IL10 IL1ra IL4/13 。s Disease Typical linear ulcers in the sigmoid (left) and aphtoid les
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