20xx年醫(yī)學(xué)專題—第四十三章人工合成抗菌藥(參考版)
2024-11-16 00:59本頁面
【正文】 磺胺類藥物是三十年代發(fā)現(xiàn)的能有效防治全身性細(xì)菌感染的第一類化療藥物,第三十五頁，共三十五頁。1. 氟喹諾酮類影響骨骼發(fā)育，孕婦及嬰幼兒慎用。喹諾酮類是含有4喹諾酮母核基本(jīběn)結(jié)構(gòu)的合成抗菌藥。1962年——Lesher 發(fā)現(xiàn)萘啶酸。ng)總結(jié),人工合成抗菌藥。,內(nèi)容(n232。,Antimicrobials are routinely added to animal feed and water to promote animal growth. Rationale is to promote more rapid growth reducing farming expenses. Mechanisms are debated although most commonly invoked is the reduction of infections, especially in unsanitary conditions. Many of the antibiotics used in this setting are of the same class as those used to treat human infections. macrolides, tetracyclines, glycopeptides,第三十三頁，共三十五頁。,Rationale for combination antibacterial therapy,To Provide broadspectrum therapy in seriously ill patients Serious infection that can not be controlled by one drug To decrease the emergence of resistant strains To decrease doserelated toxicity Meningitis and osteomyelitis caused by bacterial infection,第三十一頁，共三十五頁。,Synergetic mechanism of c
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