【正文】
22(3):2809. 虛擬 ICD: 三個策略 1. 建立計算機模型 虛擬 ICD – 依據(jù)來源于先前研究數(shù)據(jù) (PainFree II, WAVE, ENTRUST, research data on new features) 2. 驗證模型 –通過應用來自 EMPIRIC研究亞組的患者數(shù)據(jù)復制結果 (ATP, PRLogic) 3. 應用模型 將 SCDHeFT 電擊的數(shù)據(jù)應用于虛擬的ICD證實臨床可理解的性能預測 28 應用 SmartShock? 98%患者 1年內, 92%患者 5年內沒有不恰當?shù)碾姄?1 1 Virtual ICD: A Model to Evaluate Shock Reduction Strategies. Presented at HRS 2020 (P03125). SmartShock? 在確保敏感性的同時顯著減少不恰當電擊的収生 1,2 1 Predicted from Virtual ICD: A Model to Evaluate Shock Reduction Strategies. Presented at HRS 2020 (P03125). 2 Protecta Clinical Study, Medtronic data on file. 3 Poole JE, Johnson GW, Hellkamp AS, et al. Prognostic importance of defibrillator shocks in patients with heart failure. N Engl J Med. September 4, 2020。110(17):25912596. 2 Sweeney MO, et al. Differences in effects of electrical therapy type on health care utilization in the MVP ICD Trial. HRS, 2020. 4 Poole JE, et al. Heart Rhythm Society. 2020. 引起電擊的原因 SCD HeFT sample episode Poole JE, Johnson GW, Hellkamp AS, et al. Prognostic importance of defibrillator shocks in patients with heart failure. N Engl J Med. September 4, 2020。350(21):21512158. 2 Daubert JP, Zareba W, Cannom DS, et al, for the MADIT II Investigators. Inappropriate implantable cardioverterdefibrillator shocks in MADIT II: frequency, me