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iety Conference. 2020. 不必要 恰當(dāng) 不恰當(dāng) SmartShock? 減少不恰當(dāng)?shù)碾姄? 6大獨(dú)特技術(shù) Medtronic PainFREE174。350(21):21512158. 2 Daubert JP, Zareba W, Cannom DS, et al, for the MADIT II Investigators. Inappropriate implantable cardioverterdefibrillator shocks in MADIT II: frequency, mechanisms, predictors, and survival impact. J Am Coll Cardiol. April 8, 2020。22(3):2809. 虛擬 ICD: 三個(gè)策略 1. 建立計(jì)算機(jī)模型 虛擬 ICD – 依據(jù)來源于先前研究數(shù)據(jù) (PainFree II, WAVE, ENTRUST, research data on new features) 2. 驗(yàn)證模型 –通過應(yīng)用來自 EMPIRIC研究亞組的患者數(shù)據(jù)復(fù)制結(jié)果 (ATP, PRLogic) 3. 應(yīng)用模型 將 SCDHeFT 電擊的數(shù)據(jù)應(yīng)用于虛擬的ICD證實(shí)臨床可理解的性能預(yù)測(cè) 28 應(yīng)用 SmartShock? 98%患者 1年內(nèi), 92%患者 5年內(nèi)沒有不恰當(dāng)?shù)碾姄?1 1 Virtual ICD: A Model to Evaluate Shock Reduction Strategies. Presented at HRS 2020 (P03125). SmartShock? 在確保敏感性的同時(shí)顯著減少不恰當(dāng)電擊的収生 1,2 1 Predicted from Virtual ICD: A Model to Evaluate Shock Reduction Strategies. Presented at HRS 2020 (P03125). 2 Protecta Clinical Study, Medtronic data on file. 3 Poole JE, Johnson GW, Hellkamp AS, et al. Prognostic importance of defibrillator shocks in patients with heart failure. N Engl J Med. September 4, 2020。110(17):25912596. 2 Sweeney MO, et al. Differences in effects of electrical therapy type on health care utilization in the MVP ICD Trial. HRS, 2020. 4 Poole JE, et al. Heart Rhythm Society. 2020. 引起電擊的原因 SCD