【正文】
起肋間肌松弛,膈肌麻痹,病人呼吸(hūxī)停止 6. 臨床少用 其他藥物見P87,表92,第三十三頁,共三十七頁。,第三十四頁,共三十七頁。,summary,Cholinoceptor antagonists are divided into muscarinic and nicotinic subgroups on the basis of their specific receptor affinities. Atropine causes reversible blockade of cholinomimetic actions at muscarinic receptors. It does not distinguish the M1, M2, M3 subgroups of muscarinic receptors. suppresses secretion of gland Eye(dilated pupils,cannot focus for near vision) relaxes smooth muscle Cardiovascular system Central nervous system,第三十五頁,共三十七頁。,3. Anisodamine, scopolamine, homatropine, propantheline bromide, trihexyphenidyl, pirenzepine, et al. 4. Antimuscarinic agents can provide some relief relief in the treatment of common traveler’s diarrhea and urinary urgency caused by minor inflammatory bladder disorders, Some of them are used in treatment Ophthalmologic disorders, Parkinson’s disease, motion sickness, shock and cholinergic poisoning.,第三十六頁,共三十七頁。,內(nèi)容(n232。ir243。ng)總結(jié),第八章 膽堿受體阻斷藥(I)。③膽絞痛、腎絞痛效果差。治療量單獨使用(shǐy242。ng)對對血管血壓無明顯影響。(2)不易進入中樞,中樞興奮作用弱。(2)抑制腺體分泌作用阿托品,對眼和心血管作用較弱。第二節(jié) 顛茄生物堿的合成、半合成代用品。結(jié)構(gòu):屬三環(huán)類化合物,結(jié)構(gòu)與丙米嗪相似。I相阻斷、II相阻斷。Cardiovascular system,第三十七頁,共三十七頁。