20xx年醫(yī)學(xué)專(zhuān)題—多層螺旋ct肺結(jié)節(jié)和血管的關(guān)系-資料下載頁(yè)
2024-11-05 12:10本頁(yè)面
【正文】 tributing factor to type III and IV vascular morphological changes. the formation mechanism of VCS, leading to the conclusion that the course of adjacent vessels is subject to lesions, especially when diseases infiltrate the bronchiovascular bundle and interlobular septa,第三十三頁(yè)，共四十頁(yè)。,As a result , involved vessels might appear distorted, rigid or concentrated towards the lesion. Thus, it is reasonable to postulate假設(shè)(jiǎsh232。) that the vascular convergence sign commonly seen in SPNs. Actually, the type IV GGNvessel relationship resemblesVCS to some degree. The invasive adenocarcinoma group is composed of two subgroups, MIA and IAC. Subgroup analysis showed MIA and IAC had different patterns of GGNvessel relationships.,第三十四頁(yè)，共四十頁(yè)。,Type III vascular morphological changes were observed more often in the IAC than MIA subgroup, indicating that with increasing malignancy, fibre hyperplasia stimulated by malignant tissues may become more severe, and subsequently impacts on vasculature become aggravated. Further more， tumour metabolism is faster than in normal tissues。 therefore, the blood supply demanded by tumours is much higher than in normal tissues. These mechanisms indirectly lead to vessel proliferation and irregular luminal dilation.,第三十五頁(yè)，共四十頁(yè)。,Some studies have shown that endogenous and/or extrinsic tumor angiogenesis and neovascularisation could be the driving factors of vascular abnormalities observed in malignant early stage. As a CT imaging sign, VCS describes a relationship between SPNs and vessels, one or multiple vessels concentrating towards and passing through lesions or being truncated at the edge of lesions.,第三十六頁(yè)，共四十頁(yè)。,Involved vessels may appear tortuous, rigid or irregularly widening and link to pulmonary arteries or pulmonary veins. In this study, the GGNvessel relationships were categorized into four types . Statistical analysis indicated that when the relationship was type III or IV, especially type IV, it was highly likely that GGNs were malignant invasive adenocarcinoma, with MIA more than IAC. In contrast, the majority of benign and preinvasive cases was seen in type I or type II GGNvessel relationships.,第三十七頁(yè)，共四十頁(yè)。,A major drawback of this study is the limited number of cases, especially in the benign group, which may compromise the diagnostic power. Hence, a prospective clinical trial with more GGN cases is warranted to further evaluate and validate the diagnostic value of findings in this study. Additionally, this study could be strengthened if the analysis were conducted with a combination of vessel types and other GGN features, such as size and mass. Mass measurements can reflect lesion growth earlier with less variability than diameter measurements .,第三十八頁(yè)，共四十頁(yè)。,In conclusion, this study demonstrates that different GGNs might have different relationships with vessels due to variation in developmental biology and behaviour. Understanding and recognizing GGNvessel relationships in CT imaging and the strong correlation between invasive adenocarcinoma and type III and IV relationships may help identify which GGNs are more likely to be malignant.,第三十九頁(yè)，共四十頁(yè)。,內(nèi)容(n232。ir243。ng)總結(jié),Multidetector spiral CT study of the relationships between pulmonary groundglass nodules and blood vessels。Discussion,第四十頁(yè)，共四十頁(yè)。,
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