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), including 7 AAHs and 17 AISs.,第十頁,共四十頁。,Accurate differential diagnosis of GGNs will assist physicians to make treatment decisions and improve treatment outcomes and prognosis. Several investigators have suggested that analysis of relationships between SPNs and surrounding vessels can help predict the likelihood of malignancy in such nodules. The relationship between GGNs and blood vessels remains unknown. Whether this relationship can be utilised to facilitate the diagnosis of malignant GGNs is a worthy of investigation.,第六頁,共四十頁。,Multiple supplying vessels, with different originating sources, converging toward a lesion, were probably indicative of an increased blood circulation within. To further clarify affiliations of supplying vessels, we traced vascular courses slicewise backward to major vessels in the hilum . The relationships between the GGNs and supplying blood vessels were analysed in axial images, MPR images CPR images.,第十四頁,共四十頁。,The vessel(s) traveling through GGN could be artery(ies) (category A), vein(s) (category B), or artery(ies) and vein(s)(category C). There were no significant differences and correlations between vascular categories and GGN groups(p =0.50 and 0.96, respectively) .,第二十五頁,共四十頁。,A major drawback of this study is the limited number of cases, especially in the benign group, which may compromise the diagnostic power. Hence, a prospective clinical trial with more GGN cases is warranted to further evaluate and validate the diagnostic value of findings in this study. Additionally, this study could be strengthened if the analysis were conducted with a combination of vessel types and other GGN features, such as size and mass. Mass measurements can reflect lesion growth earlier with less variability than diameter measurements .,第三十八頁,共四十頁。,Type III vascular morphological changes were observed more often in the IAC than MIA subgroup, indicating that with increasing malignancy, fibre hyperplasia stimulated by malignant tissues may become more severe, and subsequently impacts on vasculature become aggravated. Further more, tumour metabolism is faster than in normal tissues。,Correlations between GGNvessel relationships and pathological findings Of 108 GGNs, type I, II, III and IV GGN vessell relationships were observed in 9, 58, 21 and 20 cases, respectively. the type II GGNvessel relationship was the dominant relationship in each pathological group, seen in 9 benign (90.0 %), 16 preinvasive (66.7 %) and 33 invasive (44.6 %) GGN cases.,第二十二頁,共四十頁。,CT imaging analysis,protocol parameters: 0.625mm section width with a 0.625mm reconstruction interval, pitch of 0.984, 120 kV and 250 mA. All images were reviewed with a highresolution , 2,0481,560pixel ,standard lung window (ww , 1,500 HU。,Abstract,Objective : To investigate the relationships between pulmonary groundglass nodules (GGN) and blood vessels and their diagnostic values in differentiating GGNs. Conclusion : Different GGNs have different relationships with vessels. Understanding and recognising characteristic GGNvessel relationships may help identify which GGNs are more likely to be malignant.,第二頁,共四十頁。 2 papillarypredominant adenocarcinomas and 1 solid predominant with mucin粘蛋白(d224。5.6 mm and 14.8177。,Some studies indicated that disease progress