【正文】
前瞻性研究完全證實( B); 3. 非鴉片類止痛劑和非甾體抗炎藥( NSAIDs)可有效治療偏頭痛( A); 4. 非藥物治療方法很少經對照研究驗證( C); 5. 如果偏頭痛發(fā)作頻率高應進行預防治療( A): ? 偏頭痛預防治療首選包括 β 受體阻滯劑( A) 美托洛爾和普萘洛爾、鈣離子拮抗劑氟桂利嗪( A)和抗驚厥藥丙戊酸( A)及托吡酯( A)。 ? 偏頭痛預防治療的二線選擇包括 β 受體阻滯劑 比索洛爾 ( B),萘普生( B)、乙酰水楊酸( C)、鎂劑( C)、艾菊( B)和阿米替林( B); ? 藥物治療還需配合非藥物治療方法包括行為治療( A)和有氧鍛煉( B); ? 偏頭痛發(fā)作頻率非常高( ≥ 3次 /月)及生活質量下降明顯的患者應接受心理治療( A)。 附:參考文獻 1. Breslau N, Rasmussen BK. The impact of migraine: Epidemiology, risk factors, and comorbidities Neurology,2023。56(Suppl 1):S4–S12. 2. Lipton RB, Bigal ME. Migraine: epidemiology, impact and risk factors for progression. Headache, 2023;45(suppl 1):s3s13. 3. Headache Classification Committee of the International Headache Society. The International Classification of Headache Disorders. Cephalalgia, 2023。24:1–160. 4. Goadsby PJ, Lipton RB, Ferrari MD. Migraine: Current understanding and treatment. NEJM,2023。 346:257270. 5. Silberstein SD. Practice parameter : evidencebased guidelines for migraine headache (an evidencebased review): report of the Quality Standards Submittee of the American Academy of Neurology for the United States Headache Consortium. Neurology, 2023。55:754762. 6. Lipton RB, Diamond S, Reed M, et al. Migraine diagnosis and treatment: results from the American Migraine Study II. Headache, 2023。41:638645. 7. Lawrence EC. Diagnosis and management of migraine headaches. Southern Med J, 2023。 97:10691077. 8. Silberstein SD, Rosenberg J. Multispecialty consensus on diagnosis and treatment of headache. Neurology, 2023。54:15531553. 9. Dowson AJ, Lipsbe S, Sender J, et al. New guidelines for the management of migraine in primary care. Curr Med Res Opin, 2023。 18:414439. 10. Ferrari MD, Roon KI, Lipton RB, et al. Triptans (serotonin, 5HT1B/1D agonists) in acute migraine treatment: a metaanalysis of 53 trials. Lancet, 2023。358:16681675. 11. Lipton RB, Stewart WF, Stone AM, et al. Stratified care vs step care strategies for migraine. JAMA,2023。284:2599–2605. 12. Snow V, Weiss K, Wall EM, et al. Pharmacologic management of acute attacks of migraine and prevention of migraine headache. Ann Intern Med, 2023; 137:840849. 致謝 《 中華內科雜志 》 編輯部 西安楊森制藥有限公司