【正文】
細(xì)胞因子TNF的表達(dá)密切相關(guān),所以我們認(rèn)為,GMCSF是特發(fā)性肺纖維化中一種重要的前炎癥因子,其具體的作用機(jī)制需要進(jìn)一步的研究。參考文獻(xiàn)(1).Kim YH, Kwon SS. Interstitial lung diseases: respiratory review of Respir Dis (Seoul). 2013 Aug。75(2):4751.(2)Suwara MI, Green NJ, Borthwick LA,et al. IL1α released from damaged epithelial cells is sufficient and essential to trigger inflammatory responses in human lung Immunol. 2013 Oct 30. doi: (3) 周賢梅,.(4) Inoue H, Nakagawa Y, Ikemura M, st analysis of acute lung injury (ALI) induced by heat exposure and/or intravenous administration of oleic Med (Tokyo). 2012 Nov。14(6):3048.(5) 林科雄,王長征,、,2000年06期.(6) Brabcova I, Kotsch K, Hribova P, et al. Intrarenal gene expression of proinflammatory chemokines and cytokines in chronic proteinuric glomerulopathies. Physiol Res. 2007。56(2):2216. Epub 2006 Mar 23. (7). 黃絮,.(8). 陳剛,吳允孚, 和GMCSF 。17(3)