β-防御素-3在耐甲氧西林金黃色葡萄球菌呼吸機相關(guān)性肺炎大鼠肺組織中的-資料下載頁
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【正文】 Biol Chem , 2001 , 276:57075713.4 Menten M , Bailey S , Debone F , et al. Pneumonia in children. J Infect Dis , 1932 , 51:254267.5 Rouby JJ , Martin De Lassale E , Poete P , et al. Nosoial bronchopneumonia in the critically ill. Histologic and bacteriologic aspects. Am Rev Respir Dis , 1992 , 146:10591066.6 Torres A , Fabregas N , Arce Y , et al. Histopathology of ventilatorassociated pneumonia (VAP) and its clinical implications. Infection , 1999 , 27:7176.7 武慶平 , 姚尚龍 , 方向明. β防御素2在呼吸機相關(guān)性肺炎中的表達(dá). 中國危重病急救醫(yī)學(xué) , 2005 , 17:353356.8 Maisetta G , Batoni G , Esin S , et al. In vitro bactericidal activity of human betadefensin 3 against multidrugresistant nosoial strains. Antimicrob Agents Chemother , 2006 , 50:806809.9 Garcia JR , Jaumann F , Schulz S , et al. Identification of a novel, multifunctional betadefensin (human betadefensin 3) with specific antimicrobial activity. Its interaction with plasma membranes of Xenopus oocytes and the induction of macrophage chemoattraction . Cell Tissue Res , 2001 , 306:257264.10 Takaoka A , Yanai H. Interferon signalling network in innate defence .Cell Microbiol , 2006 , 8:907922.11 Martin TR, Frevert CW. Innate immunity in the lungs. Proc Am Thorac Soc , 2005 , 2:403411.12 Safdar N , Crnich CJ , Maki DG. The pathogenesis of ventilatorassociated pneumonia: its relevance to developing effective strategies for prevention. Respir Care , 2005 , 50(6):725741.13 桂平 , 武慶平 , 姚尚龍 , 等. , 2008 , 17:606609.內(nèi)容總結(jié)
（1）β防御素3（BD3）是β－防御素家族中的一個成員，是上皮細(xì)胞分泌的一種重要的固有免疫效應(yīng)分子，具有廣譜高效的抗微生物活性，包括多重耐藥的金黃色葡萄球菌，BD3還能趨化單核細(xì)胞[3]
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