【正文】
ed times or creatinine=355umol/L when there was an acute rise of 44umol/L anuria for 12 h Clinical Oute Class Clinical Outes Loss Persistent ARF with a plete loss of kidney function for longer than 4 weeks Endstage Endstage renal disease for longer than 3 months renal disease ADQI workgroup Crit Care,2022 尿液中生物學(xué)標(biāo)志物 Site of injury Type Urinary biomarker Glomerular damage High molecular weight proteins Albumin transferrine immunoglobulin Impaired tubular function Low molecular weight proteins β2 microglobulin Retinal binding protein α1microglobulin Damage of proximal damage cells Brush boder markers Brush boder antigens Adenosine deaminease binding protein Carbonic anhydrase Other tublar antigens Urinary enzymes Neutral peptidase Alanine aminopeptidase Γglutamyltransferase Alkaline phosphatase Damage of distal and proximal tubular cells Cytoplasmatic markers Lactate dyhydrogenase Cathepsin B Lysosome markers NacetylβDglucosamine Βglycosidase Damage of distal tubular cells Kallikrein TammHorsfall glycoprotein 提示 ARF分型的尿液生物學(xué)標(biāo)志 ? 區(qū)別缺血 /中毒性 ARF與其他類型的 ARF 腎臟損傷分子- 1( KIM1) 鈉氫交換轉(zhuǎn)運 3型蛋白( NHE3) ? 急性同種異體移植排異反應(yīng) ARF細(xì)胞因子 白介素 白介素 白介素 18 ? 腎移植后腎功能延遲恢復(fù) 肌動蛋白 α 谷胺酰氨 S轉(zhuǎn)移酶 ( GSTs)