味精安全問題ppt課件-資料下載頁
2025-01-18 08:00本頁面
【正文】 慰劑 味精治療必須引起同樣的對(duì)味精的陽性反應(yīng)，對(duì)安慰劑沒有反應(yīng)，味精應(yīng)該以膠囊的形式給予。 ? n=19 had ≥2 symptoms in A amp。 B with MSG amp。 no symptoms with placebo. n=12 agreed to be studied. ? N=19時(shí)，實(shí)驗(yàn) A和 B的味精組都有超過 2種癥狀出現(xiàn)，安慰劑組沒有癥狀出現(xiàn)， n=12時(shí)，實(shí)驗(yàn)一致。 Protocol C Results:實(shí)驗(yàn) C結(jié)果 Geha RS et al., J Allergy Clin Immunol 106:97380, 2022 ? Two separate tests of MSG (5 g) vs placebo. ? 分開測(cè)試味精（ 5克）和安慰劑 ? n=2/12 had ≥2 symptoms with MSG amp。 none with placebo。 but symptoms were not the same. ? n=2/12， 味精組超過 2種癥狀出現(xiàn)，安慰劑組沒有癥狀出現(xiàn)，但癥狀不同。 ? n=0/130 met FASEB criteria for MSG sensitivity ? n=0/130 時(shí)符合 FASEB的 MSG過敏性實(shí)驗(yàn)標(biāo)準(zhǔn) Geha RS et al., J Allergy Clin Immunol 106:97380, 2022 CONCLUSION: Using criteria established by the 1995 FASEB panel, none of the individuals who claimed a sensitivity to MSG actually showed this sensitivity when tested under blinded conditions. 結(jié)論：根據(jù) 1995年美國實(shí)驗(yàn)生物學(xué)聯(lián)合會(huì)（ FASEB）制定的標(biāo)準(zhǔn)，對(duì)那些聲稱味精過敏的個(gè)體進(jìn)行雙盲試驗(yàn)表明他們未表現(xiàn)出敏感性。 CRS Symptoms in Humans 人體的 MSG癥狀 ? Asthma: Early studies claiming that MSG induces asthma in asthma patients have not been confirmed in recent studies involving greater numbers of patients. ? 哮喘：早期研究聲稱味精會(huì)導(dǎo)致哮喘病人病情發(fā)作，但近期眾多數(shù)量病人的研究中未得到證實(shí) Stevenson DD. Monosodium glutamate and asthma. J Nutr 130: 1067S1073S, 2022 味精和哮喘 2022年 營養(yǎng)學(xué)雜志 . MSG Symptoms in Humans 人體的 MSG癥狀 ? Urticaria: 65 subjects with idiopathic urticaria。 single and doubleblind studies using g MSG challenges vs placebo (capsules). ? 蕁麻疹：使用 （膠囊）治療 65例特發(fā)性蕁麻疹，單盲和雙盲研究 ? “ ..MSG is a distinctly unmon cause or exacerbant of chronic urticaria, if it induces urticaria at all. We were certainly unable to demonstrate MSGinduced urticaria in any of our chronic urticaria patients, even those who believed MSG provoked their urticaria in the past.” ? 即使味精會(huì)引發(fā)蕁麻疹，那也很少會(huì)引起或加劇慢性蕁麻疹。我們無法確證慢性麻疹病人中多少是由味精所致的，盡管有些人認(rèn)為是因?yàn)檫^去食用味精所致病。 Simon RA. Additiveinduced urticaria: Experience with monosodium glutamate (MSG). J Nutr 130: 1063S1066S, 2022. Bazzano G, D39。Elia JA, Olson RE Science 169: 12081209, 1970. Adult human subjects ingested a chemicallydefined diet supplying all of the essential amino acids in optimum amounts, plus glutamic acid as the sole source of nonessential nitrogen, for 1442 days. No subjects developed the Chinese restaurant syndrome. No changes in weight, irritability, appetite or mentation were noted. 給予成人研究對(duì)象適量的化學(xué)性飲食包含所有必須氨基酸 ， 并以谷氨酸作為非必須氮源 ， 1442天后 ， 沒有發(fā)現(xiàn)中國餐館綜合癥 ， 體重 、 情緒 、 胃口以及智力都沒有變化 。
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