味精安全問題ppt課件(編輯修改稿)
2025-02-14 08:00 本頁面
【文章內(nèi)容簡介】 his dose raised plasma GLU from 45 nmol/ml to peak values of about 300 nmol/ml in 3045 min. From: Baker GL et al., Factors influencing dicarboxylic amino acid content of human milk. In: Glutamic Acid: Advances in Biochemistry amp。 Physiology, Filer LJ et al., ed. New York, Raven Press, 1979 , pp. 111123. 哺乳期女性加水攝入 100 mg/kg 的膠囊 ， 對其后特定時間的母乳樣品進行檢驗表明： 這一劑量使得血液谷氨酸濃度在 3045分鐘內(nèi)從 45nmol/ml 提高到峰值約300 nmol/ml 。 From: Baker GL et al., Factors influencing dicarboxylic amino acid content of human milk. In: Glutamic Acid: Advances in Biochemistry amp。 Physiology, Filer LJ et al., ed. New York, Raven Press, 1979 , pp. 111123. 影響人體母乳二氨基酸濃度的因素 谷氨酸：生物化學和生理學進展 Brain Issues 大腦問題 ? Relevance to human MSG ingestion: ? 有關人體攝入味精 ? The placenta blocks GLU transfer from maternal into fetal blood: FETAL brain is safe. ? 胎盤會阻止谷氨酸從母體傳遞給胎兒：胎兒大腦不會受到影響 ? Breast milk (GLU) does not rise when mother ingests highdose MSG: NEWBORN/INFANT brain is safe. ? 當母體攝入大劑量的味精母乳中的谷氨酸含量不會上升：新生兒的腦發(fā)育是安全的 ? Infant metabolizes GLU at same rate as adult (Stegink et al., Pediatric Res 20: 5358, 1986). ? 嬰幼兒具有和成年人同樣的谷氨酸代謝的能力 Brain Issues大腦問題 ? The human brain is unaffected by the very high plasma (GLU) following high dose MSG intake ? 攝入大量的味精導致的血漿中高谷氨酸含量不會對人體大腦產(chǎn)生影響 ? No dose of MSG has yet been given to humans high enough to induce CNS effects. ? 至今亦未發(fā)現(xiàn)食用味精會影響人體中樞神經(jīng)系統(tǒng) CRS/Allergy (MSG Symptom Complex) 中國餐館綜合癥 /過敏癥 味精綜合癥 Studying MSG Symptom Complex 味精綜合癥研究 ? Can reproducible symptoms be defined? ? 能定義這些重復性的癥狀么？ ? Are reproducible symptoms doserelated? ? 這些重復性癥狀與攝入劑量有關嗎 ? ? Do MSGsensitive individuals exist? ? 對味精敏感的個體存在嗎？ SYMPTOMS ATTRIBUTED TO MSG:味精所致癥狀 ? Burning, tightness, numbness in upper chest, neck and face. 發(fā)燒，身體發(fā)緊，胸腔上部發(fā)悶，脖子、面部發(fā)麻 ? Dizziness, headache 眩暈，頭疼 ? Chest pain, palpitation 胸口痛，心悸 ? Weakness 乏力 ? Nausea, vomiting 反胃嘔吐 ? Bronchospasm (asthmatics)哮喘 ? Hives (urticaria)麻疹 MECHANISMS UNKNOWN 機制未知 Multicenter, doubleblind, placebocontrolled, multiplechallenge evaluation of reported reactions to monosodium glutamate. Geha RS et al. J Allergy Clin Immunol 106:97380, 2022 味精反應的多中心、雙盲、安慰劑控制、多重治療評估報告 2022年 過敏與臨床免疫學 雜志 ? Protocol A: 130 selfstyled MSGsensitive individuals. Fasted, challenge blind with placebo or MSG (5 g in liquid). ? 實驗 A： 130例自認為 MSG過敏者，禁食，以安慰劑或 MSG(5克液體 )進行盲試。 ? Protocol B:
試題試卷相關推薦
鄂ICP備17016276號-1