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(~) ? nVLFP。 % (~) (~) ? LFP/HFP。 % (~) (~) ? _________________________________________________________________________ ? ? Data are presented as medians (25 percentile~75 percentile) ? *p vs. Controls。 ? p vs. Controls. ? Table 52. Percentage changes in HRV measures, blood biochemistry, lipid profile and cytokine levels of the controls and TCC trainees ? _____________________________________________________________________ ? Measures Controls TCC Trainees ? _____________________________________________________________________ ? Blood tests ? FBS。 % (~) (~)* ? TG。 % (~) (~) ? TC。 % (~) (~)? ? LDLC。 % (~) (~) ? HDLC。 % (~) (~) ? TC/HDLC。 % (~) (~)? ? LDLC/HDLC。 % (~) (~) ? UA。 % (~) (~) ? TNFα。 % (~) (~)? ? IFNγ。 % (~) (~)? ? _________________________________________________________________________ ? ? Data are presented as medians (25 percentile~75 percentile) ? *p vs. Controls。 ? p vs. Controls. Discussion Discussion TCC have beneficial effects on the cardiorespiratory function 1. twoyear practicing TCC regularly may delay the decline of cardiorespiratory function in older individuals. (Lai et al. J Am Geriatr Soc 1995。43:12227) 2. 12month TCC program was effective in improving cardiorespiratory function, muscle strength, and flexibility in the elderly. (Lan et al. Med Sci Sport Exerc 1998。30:34551) ? The FEV1/FVC of the TCC trainees was increased significantly after 3 months of TCC training. TCC have beneficial effects on the cardiorespiratory function 3. 12 weeks of exercise in mild hypertensive patients reduced blood pressure and favorable changes of lipid profile. (Tsai et al. Clin Exp Hyper 2020。24:31524) 4. TC/HDLC, LDL/HDL ratios were associated with coronary heart disease risk. (Arsenault et al. Eur J Clin Invest 2020。40:108193) ? The HDLC increased significantly, the TC was decreased significantly, TC/HDLC decreased significantly after 3 months of TCC training. TCC exercise might benefit immunoregulatory function of the subjects 1. Endurance athletes activate antileukemic immunity and that TNFα and IFNγ were much higher pared to the controls. (Chiang et al. Int J Sports Med 2020。21:6027) 2. TCC for two months significantly increase the level of IgG. (Zhang et al. J Beijing Inst Phys Edu 1990。4:124) 3. The number and activity of natural killer cells significantly increased after the practice of Wu’s TCC . (Li and Shen. Chin J Sports Med 1995。14:536) TCC exercise might benefit immunoregulatory function of the subjects 4. Circulating T cells, active T lymphocytes all significantly higher in the TCC practitioners. (Sun et al. J Sports Med 1989。10:2179) 5. TCC exercise increase CD4CD25 regulatory Tlymphocytes in type 2 diabetic patients. (Yeh et al. Diab Care 2020。30:7168) 6. TNFα possessed antitumor and immunomodulation, IFNγ plays an important role in the growth and differentiation of cytotoxic T cells, activates NK cells and B cell maturation factor. (Lans et al. Anticancer Res 2020。24:22438。 Ohno et al. Int J Hematol 2020。77:28694) Conclusion ? Three months of TCC training can improve the pulmonary function, glucose availability and blood lipid profile, as well as increase the cytokine production in middleaged and elderly subjects. ? TCC may be beneficial to the middleaged and elderly people as a healthpromoting calisthenics. ?研究成果 ? WanAn Lu, ChengDeng Kuo. Effect of 3Month Tai Chi Chuan on Heart Rate Variability, Blood Lipid and Cytokine Profiles in MiddleAged and Elderly Individuals. Int J Gerontol. 2020 March。 6(4):267272. Thanks for your attention