wangjin靜脈麻醉和tci(編輯修改稿)
2025-02-08 08:34 本頁(yè)面
【文章內(nèi)容簡(jiǎn)介】 the blood and firstpass pulmonary uptake. The peripheral partments are posed of tissues and ans that show a time course and extent of drug accumulation (or dissipation) different from that of the central partment. In the threepartment model, the two peripheral partments may correspond roughly to splanchnic and muscle tissue (rapidly equilibrating) and fat stores (slowly equilibrating). 效應(yīng)室 effect keo V 1 V 2 V 3 k 12 k 21 k 13 k 31 DOSIS k 10 幾個(gè)有用的藥代 藥效學(xué)概念 1. ke0與 t1/2ke0 ? 藥物的 ke0 越大，其 t1/2ke0越小，說(shuō)明該藥物峰值效應(yīng)出現(xiàn)快 2. T1/2cs： 持續(xù)輸注后半衰期，時(shí) 量相關(guān)半衰期 ? 反映效應(yīng)室藥物的清除速率，用于預(yù)測(cè)麻醉后的恢復(fù)時(shí)間 ? T1/2cs越小，停藥后蘇醒越快 3. 平均有效時(shí)間 （ mean effect time）： ?
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