豬肺炎支原體的免疫時(shí)機(jī)及疫苗的選擇(編輯修改稿)
2025-02-02 06:11 本頁面
【文章內(nèi)容簡介】 Control Management factors (continued) ? Segregated Early Weaning (SEW) has shown merit ? 早期隔離斷奶也有一定好處 ? Vaccination免疫 ? Optimize density and proper ventilation ? 合理化密度，保持良好通風(fēng) 29 M. hyo Prevention and Control Key to an effective program to control PRDC (Porcine Respiratory Disease Complex) is an effective M. hyo vaccine 控制 PRDC有效措施的關(guān)鍵是使用有效的支原體疫苗 30 M. hyo Vaccines ? Because the exact antigenic epitopes responsible for immunity are not well understood, wholecell vaccines are best. ?因?yàn)檫€不清楚決定免疫力的具體抗原決定部位，所以全細(xì)胞疫苗是最好的。 31 Western Blot Analysis 免疫印記分析 ? M+Pac preserves 15 proteins ?安百克保留了 15種抗原蛋白 ? Product A preserves 11 proteins ? A產(chǎn)品保留了 11種抗原蛋白 ? Products B and C preserve 8 proteins ? B和 C產(chǎn)品保留了 8種抗原蛋白 32 M+PAC 安百克 擁 有全世界最多的 豬支原體 抗原 Pfizer Intervet Fort Dodge M+PAC 33 M. hyo Vaccines ? Also, because longlasting immunity is important, it is our belief that an effective M. hyo vaccine should have an improved oil adjuvant….. ? 此外，長久免疫力是重要的，良好的油佐劑是支原體疫苗必須的。 34 Vaccine Adjuvants 疫苗佐劑 35 Vaccine Adjuvants 疫苗佐劑 ? Aluminum Hydroxide (AH)氫氧 化鋁 ? Waterinoil (W/O)油包水 ? Oilinwater (O/W)水 包油 36 Aluminum Hydroxide 氫氧化鋁 ? Low viscosity粘度 低 ? Mild to no reactions溫和 無刺激 ? Immediate response免疫 反應(yīng)迅速 ? Shortlived immunity免疫 期短 37 WaterinOil (W/O)油包水 ? More oil = more viscosity粘度 高 ? More irritation刺激 大 ? More pain疼痛 ? More stress應(yīng)激 大 38 OilinWater (O/W)水包油 ? More modern最 新型 ? At least as effective as W/O與 油包水效果相同 ? Less oil = lower viscosity低 粘度 ? Less irritation刺激 小 ? Less pain疼痛 少 ? Less stress (pigs and people)應(yīng)激 小 39 M. hyo Vaccine Adjuvants ? M+PAC174。 SPAH O/W+AH ? Respisure174。 Pfizer O/W,Lecithin卵磷脂 ? Respifend174。 Fort Dodge AH ? Ingelvac MH Nobl/BI W/O ? Porcilis Intervet AH ? Hyor
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