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【正文】 ere used to infer autonomic modulation through measures of heart rate variability (HRV). Probabilistic independent ponent analysis was used to separate resting fMRI data into DMN and SMN ponents. Following verum, but not sham, acupuncture there was increased DMN connectivity with pain (anterior cingulate cortex (ACC), periaqueductal gray), affective (amygdala, ACC), and memory (hippocampal formation, middle temporal gyrus) related brain regions. Furthermore, increased DMN connectivity with the hippocampal formation, a region known to support memory and interconnected with autonomic brain regions, was negatively correlated with acupunctureinduced increase in a sympathetic related HRV metric (LFu), and positively correlated with a parasympathetic related metric (HFu). Following verum, but not sham, acupuncture there was also increased SMN connectivity with painrelated brain regions (ACC, cerebellum). We attribute differences between verum and sham acupuncture to more varied and stronger sensations evoked by verum acupuncture. Our results demonstrate for the first time that acupuncture can enhance the poststimulation spatial extent of resting brain works to include antinociceptive, memory, and affective brain regions. This modulation and sympathovagal response may relate to acupuncture analgesia and other potential therapeutic effects. 按 MIAs分段閱讀 ?Previous studies have defined lowfrequency, spatially consistent works in resting fMRI data which may reflect functional connectivity. We sought to explore how a plex somatosensory stimulation, acupuncture, influences intrinsic connectivity in two of these works: the default mode work (DMN) and sensorimotor work (SMN). We analyzed resting fMRI data taken before and after verum and sham acupuncture. Electrocardiography data were used to infer autonomic modulation through measures of heart rate variability (HRV). Probabilistic independent ponent analysis was used to separate resting fMRI data into DMN and SMN ponents. Following verum, but not sham, acupuncture there was increased DMN connectiv
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