【正文】 before and after verum and sham acupuncture. Electrocardiography data were used to infer autonomic modulation through measures of heart rate variability (HRV). Probabilistic independent ponent analysis was used to separate resting fMRI data into DMN and SMN ponents. Following verum, but not sham, acupuncture there was increased DMN connectivity with pain (anterior cingulate cortex (ACC), periaqueductal gray), affective (amygdala, ACC), and memory (hippocampal formation, middle temporal gyrus) related brain regions. Furthermore, increased DMN connectivity with the hippocampal formation, a region known to support memory and interconnected with autonomic brain regions, was negatively correlated with acupunctureinduced increase in a sympathetic related HRV metric (LFu), and positively correlated with a parasympathetic related metric (HFu). Following verum, but not sham, acupuncture there was also increased SMN connectivity with painrelated brain regions (ACC, cerebellum). We attribute differences between verum and sham acupuncture to more varied and stronger sensations evoked by verum acupuncture. Our results demonstrate for the first time that acupuncture can enhance the poststimulation spatial extent of resting brain works to include antinociceptive, memory, and affective brain regions. This modulation and sympathovagal response may relate to acupuncture analgesia and other potential therapeutic effects. ① Acupuncture modulates resting state connectivity in default and sensorimotor brain 軀體感覺腦網(wǎng)絡的靜息狀態(tài)的連通性 ② Previous studies have defined lowfrequency, spatially consistent works in resting fMRI data which may reflect functional connectivity. 先前研究已用反映（人腦）功能連通性的 fMRI 數(shù)據(jù)來定義低頻空間連續(xù)性網(wǎng)絡。 ⑨ Following verum, but not sham, acupuncture there was also increased SMN connectivity with painrelated brain regions (ACC, cerebellum). 在真而非偽針灸后，感覺運動網(wǎng)絡（ SMN）與疼痛相關腦區(qū)（扣帶皮層前部與小腦）的連通性增加。 ⑥ Probabilistic independent ponent analysis was used to separate resting fMRI data into DMN and SMN ponents. 利用概率獨立元分析把靜息 fMRI數(shù)據(jù)分為默認狀態(tài)網(wǎng)絡（ DMN）和感覺運動網(wǎng)絡（ SMN）