【正文】 學(xué)號：022070082022 屆本科生畢業(yè)論文（設(shè)計）題 目：年產(chǎn) 1000 噸蘇云金芽孢桿菌的發(fā)酵車間工藝設(shè)計 學(xué)院(系)： 植保學(xué)院專業(yè)年級： 制藥071學(xué)生姓名： 白威指導(dǎo)教師： 陳光友 講師合作指導(dǎo)教師： 無完成日期： 目 錄摘 要 ...........................................................................................................................................IABSTRACT ..............................................................................................................................II第 1 章 緒論 ...............................................................................................................................1 項目背景 ...........................................................................................................................................1 蘇云金芽孢桿菌介紹 .......................................................................................................................1 蘇云金芽孢桿菌定義 ...........................................................................................................1 蘇云金芽孢桿菌資源 ...........................................................................................................1 蘇云金芽孢桿菌鑒定與分類 ...............................................................................................2 孫云錦芽孢桿菌生態(tài)學(xué)及安全性 .......................................................................................3 蘇云金芽孢桿菌產(chǎn)品化 .......................................................................................................3 設(shè)計方案 ...........................................................................................................................................4 產(chǎn)品方案 ...............................................................................................................................4 選址 .......................................................................................................................................5 車間生產(chǎn)過程設(shè)計 ...............................................................................................................5第 2 章 工藝流程確定與論證 ...................................................................................................6 工藝流程確定 ...................................................................................................................................6 蘇云金芽孢桿菌液體深層發(fā)酵 ...........................................................................................6 蘇云金芽孢桿菌固態(tài)發(fā)酵 ...................................................................................................7 小結(jié) .......................................................................................................................................8第 3 章 物料衡算 .......................................................................................................................9 生產(chǎn)條件 ...........................................................................................................................................9 各設(shè)備的物料衡算 ...........................................................................................................................9 發(fā)酵罐物料衡算 ...................................................................................................................9 接種罐物料衡算 .................................................................................................................10 過濾后的物料橫算 .............................................................................................................11 干燥后的物料衡算 .............................................................................................................12第 4 章 能量衡算 .....................................................................................................................13 熱量衡算基礎(chǔ)數(shù)據(jù)的計算和查取 ................................................................................................14 比熱容的計算 .......................................................................................................................14 狀態(tài)熱的計算 ......................................................................................................................14 化學(xué)反應(yīng)熱的計算 ..............................................................................................................15 熱量衡算 .........................................................................................................................................17 反應(yīng)過程的熱量衡算 ...........................................................................................................17 過濾和離心過程的熱量衡算 ...............................................................................................19 產(chǎn)品干燥崗位的熱量衡算 ...................................................................................................20第 5 章 設(shè)備確定及選型 .........................................................................................................22 發(fā)酵罐的設(shè)計 ................................................................................................................................22 發(fā)酵罐的尺寸設(shè)計 ............................................................................................................22 發(fā)酵罐攪拌器軸功率計算 ................................................................................................23 種子罐的計算 ................................................................................................................................24 種子罐的尺寸計算 .............................................................................................................24 種子罐軸功率計算 ............................................................................................................25 發(fā)酵液的貯罐計算 ........................................................................................................................25 過濾器的選擇 .................................................................................................................................25 離心機的選擇 ..................................................................................................