腫瘤分子靶向治療的思考(已修改)
2025-06-07 18:14 本頁面
【正文】 BATTLE PROGRAM ? Biomarkerbased Approach of Targeted Therapy for Lung Cancer Elimination. Waun Ki Hong et al ? Biomarker Analysis in Core Biopsy ? Select Adequate Target Therapy 未來的方向 ?加強癌癥基因分型及藥物基因學研究，尋找各種靶向治療藥物的適用或預測指標。 ? Treating tumors according to their molecular defects and their upgraded or downgraded signal transduction pathways. Clinical Predictors of Gefitinib or Erlotinib Efficacy in NSCLC ? Never smoker ? Female gender ? Adenocarcinoma ? Bronchoalveolar adenocarcinoma ? Asian origin 腫瘤分子靶向治療的思考 中山大學腫瘤防治所 管忠震 分子靶向治療研究的興起 ?上世紀 7080年代，癌癥生物學研究迅速發(fā)展，從分子水平了解腫瘤發(fā)生、發(fā)展的機制。 ? Scientific research has increasingly identified key geic events critical to specefic cancer development. Targeting Therapy ? A new generation of small molecules or MABs that rationaly designde to inhibit specific signal transduction or transcription pathways that are critical for cancer cell growth and survival. EGFR Blockade as Cancer therapy ? The EGFR autocrine pathways plays an important role i
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