【正文】
醫(yī)院獲得性 NFGNB感染的 治療與控制 復(fù)旦大學(xué)附屬中山醫(yī)院 上海市院內(nèi)感染質(zhì)控中心 何禮賢 The Impact of Antim icrobial Res istant Gram Nega ti ve Infecti onsThe Impact of Antim icrobialThe Impact of Antim icrobial istant Res istant Gram ti ve InfectiNega ti ve Infecti ons? Re sistan ce to an timicr ob ia l ag en ts is incr ea sin g am on g m an y gr am ne ga tive p ath og en s1? Infe ction with re sistan t pa tho ge ns is a ssoci ate d with ne ga tive h ea lth o utco me s3 ,4– Mor tal ity/mor bi di ty– Le ng th of I CU and hosp ita l stay– He al thcar e costs? No ne w a ntib io tic classe s un de r d eve lo pm en t2– Highlight s t he need t o opt imiz e ex i st ing clas ses of an timi crob ia ls1 . Ga y n e s R , e t a l . C l i n I n fe c t D i s . 2 0 0 5 。4 1 :8 4 8 8 5 4 . 2 . S p e l l b e rg B , e t a l . C l i n In fe c t D i s . 2 0 0 4 。3 8 :1 2 7 9 1 2 8 6 . 3 . L a u te n b a c h E , e t a l . In fe c t C o n tro l H o s p E p i d e m i o l . 2 0 0 6 。2 7 :8 9 3 9 0 0 . 4 . C o s g ro v e , S e t a l . C l i n In fe c t D i s . 2 0 0 6 。4 2 :S8 2 S 8 9 . . Per cent age o f Noso ial Inf ectio ns Associat ed With Selected Pathog ens, 2 003Per cent age o f Noso ial Inf ectio ns Per cent age o f Noso ial Inf ectio ns Associat ed With Selected Pathog ens, 2 003Associat ed With Selected Pathog ens, 2 003E col i , %En te r o b ac te rspp , %P ae r u g i n o sa , %Surgi ca l si te in fe ct io n(n = 29 84 )Ur in ary t r ac t in fe ct io n(n = 41 09 )Blo o d st r ea m in fe ct io n(n = 23 51 )Pne u m o n ia(n = 43 65 )Ac i n et o b ac te r spp , %K p n eumon i ae , %T y p e o f In fe ct io nDa ta from th e Na ti o n a l No s o c o m i a l In fe c ti o n s S u rv e i l l a n c e (NNI S ) S y s te m , 2 0 0 3 . P e rc e n ta g e s o f b a c te ri a l IC U is o l a te s a re sho wn .Ga y n e s R , E d w a rd s JR. C l i n In fe c t D i