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新生兒肺出血-lyjppt課件(已修改)

2025-01-31 22:06 本頁(yè)面
 

【正文】 新生兒肺出血 ? 概述 ? 臨床表現(xiàn) ? 早期診斷線索 ? 診斷及鑒別診斷 ? 預(yù)防 概述( 1) ● 發(fā)病率 活產(chǎn)嬰兒的 15%(尸檢的 140%) 與胎齡有關(guān) ● 6% of infants 1700 g (Garland 1994) – 19891992 (US) ? 12% of 1500 g infants (Pandit 1999) – 19901994 (Canada) ? 15% of 1250 g infants (Baier 2022) – 19971998 (US) Pandit et al 1999 概述( 2) ● 發(fā)病時(shí)間 2個(gè)高峰時(shí)間 (生后第一天;生后 67天) ● 死亡率 5080% ● 預(yù)后 ? Pandit et al 1999 – All degrees of PH ? Severity based on FiO2 increment – Mild and Severe – Mortality ? 15% moderate ? 64% severe – BPD ? 64% (moderate and severe) ? Baier et al 2022 – Clinically significant PH (moderate–severe) – Mortality 27% ? Majority from respiratory failure ? Not acutely – BPD ? 50% of survivors ? Greatly increased duration of MV and oxygen ? 100% were on Oxygen at 28 days – Survival without BPD ? 33% – CNS morbidity increased ? IVH 53% ? Increased severity of IVH ? PVL 13% Alfaleh K, Pediatrics. 2022 臨床表現(xiàn) ? 原發(fā)病表現(xiàn) ? 全身癥狀 ? 呼吸障礙 原發(fā)病癥狀基礎(chǔ)上臨床表現(xiàn)突然加重 Acute deterioration of patient who was improving post surfactant ? 出血表現(xiàn) 鼻腔、口腔流出或噴出血性液體,或于氣管插管后流出或吸出泡沫樣血性 ? 肺部體征 : 呼吸音減低或
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