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尿病診斷新標(biāo)準(zhǔn)的診斷價(jià)值_張-閱讀頁

2024-09-05 11:06本頁面
  

【正文】 滿意,對(duì)降低母兒并發(fā)癥,提高預(yù)后有顯著意義。本資料中B組較A組、C組妊娠期高血壓疾病發(fā)生率稍高,其中A組妊娠期高血壓疾病6例,輕度子癇前期6例,B組妊娠期高血壓疾病9例,輕度子癇前期7例,但差異無統(tǒng)計(jì)學(xué)意義(P>),可能與納入本研究的患者均為輕型GDM有關(guān)或樣本量較少有關(guān)。 關(guān)于妊娠期糖尿病診斷標(biāo)準(zhǔn)的探討新標(biāo)準(zhǔn)較舊標(biāo)準(zhǔn)診斷的妊娠期糖尿病發(fā)患率增加23倍[7],增加的病患多為輕度妊娠期糖尿病患者,導(dǎo)致大量的醫(yī)療資源被卷入。因此認(rèn)為把注意力集中在輕型GDM患者是放錯(cuò)了位置,建議對(duì)新標(biāo)準(zhǔn)的實(shí)行應(yīng)進(jìn)行風(fēng)險(xiǎn)、成本、收益的評(píng)估。有學(xué)者提出,糖化血紅蛋白含量以客觀地反映取血前4 ~ 8 周血糖平均情況,與血糖的暫時(shí)性波動(dòng)、抽血時(shí)間及抽血前代謝波動(dòng)等干擾因素?zé)o關(guān),近年來,國際上逐漸達(dá)成推薦使用HbA1c 對(duì)GDM 進(jìn)行診斷和檢測[9],但需進(jìn)一步確定其診斷切點(diǎn)值。本資料表明, 2010年IADPSG標(biāo)準(zhǔn)較為嚴(yán)格, 會(huì)使納入人群增加,降低漏診率,但可以明顯降低母、兒合并癥的風(fēng)險(xiǎn)。因?yàn)樘谴x對(duì)母體的影響是逐漸的和連續(xù)的, 故不應(yīng)期待一個(gè)唯一的血糖閾值就能夠把正常和異常糖代謝的孕婦完全分開。參考文獻(xiàn)[1] Bellamy L,Casas JP,Hingorani AD,et 2 diabetes mellitus after gestational diabetes:a systematic reviewand meta-analysis[ J] .Lancet,2009,373:1773-1779.[2 ]International Association of Diabetes and Pregenancy StudyGroups Consensus Panel,Metzger BE,Gabbe SG, association of diabetes and pregancystudy groups remend ations on the diagnosis and classification of hyperglycemia in pregancy[ J] .Diabetes Care,2010,33:676-682.[3 ][M].第7 : .[4] Bellamy L,Casas JP, Hingorani A D, et al. Type 2 diabetes mellitus after gestational diabetes: a systematic review and metaanalysis[ J] . Lancet, 2009, 373 ( 9677) : 1773 9.[5]Landon MB,Spong CY,Thom E,et multicenter,randomized trial of treatment for mild gestational diabetes[ J].N Engl J Med,2009,361:1339-1348.[6] ReyesMunoz E,Parra A,CastilloMora A, et of the diagnostic criteria of the International Association of Diabetes and Pregnancy Study Groups on the prevalence of gestational diabetes mellitus in urban Mexican women: a crosssectionalstudy[J].。rkrid, Line Sletner,et al. Impact of ethnicity on gestational diabetes identified with the WHO and the modified International Association of Diabetes and Pregnancy Study Groups criteria: a populationbasedcohort tudy[J].European Journal of Endocrinology .2012,166 :17–324.[8] Cundy T. Proposed new diagnostic criteria for gestational diabetesa pause for thought? Diabetes medicine,2012, Fe
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