【正文】
o Haiyan,Luo Yufen, Yang Min(Guangdong General Hospital, Guangdong Academy of Medical Scientices, Guangzhou, Guangdong 510080, China)ABSTRACT OBJECTIVE: To analyze the effect of intervention on perioperative antibiotics prophylaxis in neurosurgery. METHODS: 200 neurosurgery cases before intervention were sampled randomly as control group and 200 neurosurgery cases after intervention were sampled randomly as intervention group. Investigation and analysis were performed in the perioperative antibiotics prophylaxis. RESULTS: Compared with the control group, rationalities of perioperative antibiotics prophylaxis in the intervention group were significantly increased and irrationalities were significantly decreased. The average duration of antibiotic prophylaxis in the intervention group was significantly shorter than the control group. There was no significant difference in the incidence of surgical site infection between two groups. CONCLUSION: The implementation of rational drug use interventions is effective and feasible. It contributes to promoting the rational use of perioperative antibiotics prophylaxis in neurosurgery.Keywords:Perioperative。結(jié)果:與對照組相比,干預(yù)組圍手術(shù)期預(yù)防用抗菌藥物合理性方面顯著改善,不合理用藥指標(biāo)顯著降低,平均預(yù)防用藥時(shí)間顯著縮短,而兩組間手術(shù)部位感染發(fā)生率無顯著差異。神經(jīng)外科圍手術(shù)期預(yù)防性使用抗菌藥物干預(yù)效果分析張曉娟,陳彩萍,萬波,勞海燕,羅宇芬,楊敏(廣東省人民醫(yī)院藥學(xué)部 廣東省醫(yī)學(xué)科學(xué)院,廣東 廣州 510080)摘要: 目的:評(píng)價(jià)干預(yù)措施對我院神經(jīng)外科圍手術(shù)期預(yù)防性使用抗菌藥物的有效性和可行性。方法:隨機(jī)抽