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thelial Cl? conductance under basal conditions. ? Second, nonCF epithelia had some constitutive CFTR Cl? Conductance under basal conditions. ? Third, the measurements of Gt, apical Na+ current, and 22Na+ ?uxes indicate that Na+ conductance in CF epithelia did not exceed that in nonCF epithelia. ? Fourth, the paper found that basal Vt, ΔVtamil and ΔIscamil were greater in CF than in nonCF epithelia. Thank you! 婁本光 2022113 。 上皮細(xì)胞 ? 生物體內(nèi)依靠不同組織系統(tǒng)的作用有選擇性地將必須的非電解質(zhì)和 電解質(zhì) 從外環(huán)境吸收或者從內(nèi)環(huán)境分泌出去,所有這些組織系統(tǒng)由大量形態(tài)較規(guī)則,排列緊密的細(xì)胞組成,這些多面體細(xì)胞組成的幾乎沒有細(xì)胞間質(zhì)的薄層稱之為上皮。 離子替代法 ? 把正常 KH溶液中的某種離子替換掉(如 Cl用葡萄糖酸根替代),看此時加藥后的反應(yīng)比起在正常 KH中的反應(yīng)是否有變化。這種模式用于測定由上皮主動轉(zhuǎn)運的離子。 ? 鉗制模式 1. 電流鉗模式-跨上皮電流被鉗制在 0μA,測量細(xì)胞兩側(cè)的電勢差。108(25):102605. Michael J. Welsh, . Professor of Medicine, Molecular Physiology and Biophysics, and Neurosurgery Roy J. Carver Biomedical Chair in Internal Medicine Investigator, Howard Hughes Medical Institute Director, Pappajohn Institute Di