【正文】
Na+ unidirectional and Na+ ?ux rates . Observations about Isc . . Observations about Vt . ?Conclusion: Amiloride causes greater Vt and Isc changes in CF Epithelia Excised NonCF Epithelia Show Properties Similar to Those in Cultured Epithelia. . ?Paradoxical Finding: ΔVtamil and ΔIscamil Not Na+ Conductance Increased in CF. ? Conclusion: CF/nonCF differences in Basal Vt, ΔVtamil, and ΔIscamil ? . . Values of basal Vt, ΔVtamil,and ΔIscamil did not exceed or were only slightly greater than those in nonCF . In Cl?free solutions,basal Vt, ΔVtamil,and ΔIscamil did not differ between CF and ?free solutions reduced basal Isc in both nonCF and CF Effects of CFTRinh172 . Gt :Same in nonCF and CF . Discussion ? CF Airway Epithelia Have Reduced Anion Conductance but Not Increased Na+ Conductance. ? The data allow four main conclusions about electrolyte transport in CF vs. nonCF airway epithelia. ? First, CF airway epithelia have a markedly reduced transepi