生物技術(shù)藥物,12。stemcell-文庫(kù)吧資料
2025-01-14 02:16本頁(yè)面
【正文】 womb. The resulting stem cells can potentially develop into specialized cells that are useful for treating severe illnesses. International Legislation ? Embryonic Stem cell research is highly controversial not only in the United States but worldwide. ? In the past two years, many nations have begun to tolerate, if not to support, the research. ? In the fall of 2022, the United Nations will consider enacting a global ban on both therapeutic and reproductive cloning. Stem Cell Research Worldwide United Nations ? In November 2022, a mittee of the General Assembly defeated by only one vote a proposal to ban therapeutic cloning research. The United States delegation strongly supported this proposal. ? In September 2022, the General Assembly will again consider the proposal to ban the research. 2022。 Regenerative Medicine Science of Stem Cells? ? Stem cell research has potential to contribute to new therapies and improved quality of life. ? Late 1998 a group of scientists, led by James Thomson, at UW Madison were the first to isolate and culture human embryonic stem cells. ? Revolution in medicine amp。 Regenerative Medicine Transgenic Animals Transgenic Animals Outline ? Why develop transgenic animals? ? How are heterologous genes introduced and expressed in animal systems? ? Can animals be cloned? ? What is the current technology in animal transgenesis? ? What are the applications of transgenic animal technology? Transgenic Animals Why? ? Selective breeding has been used over many generations to geically improve animals for desirable traits ? Breeding pure lines is timeconsuming and costly ? Introduction of a new trait into a pure breeding line is difficult ? Limited by naturally occurring traits Transgenic Animal Applications ? Geic engineering of desirable traits ? Rapid creation of pure breeding lines and identical offspring (clones) ? Animal model systems for research in human diseases ? Animal systems as bioreactors for production of heterologous biological molecules (“pharming”) How to Introduce Foreign Genes Basic Strategy ? Inject a cloned gene into the nucleus of a fertilized egg ? Implant the geically engineered egg into a receptive femal
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