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tolerate combination chemotherapy well, such as those in poor overall health. If the initial chemotherapy treatment is no longer working, secondline treatment usually consists of a single drug such as docetaxel or pemetrexed. Another option may be the targeted therapy erlotinib (Tarceva) Again, advanced age is no barrier to receiving these drugs as long as the person is in good general health.,NSCLC Chemotherapy,Possible side effects,Chemotherapy drugs work by attacking cells that are dividing quickly, which is why they work against cancer cells. But other cells in the body, such as those in the bone marrow, the lining of the mouth and intestines, and the hair follicles, also divide quickly. These cells are also likely to be affected by chemotherapy, which can lead to side effects. The side effects of chemotherapy depend on the type and dose of drugs given and the length of time they are taken. These side effects can include:,Possible causes,side effects,hair loss mouth sores loss of appetite nausea and vomiting increased chance of infections (due to low white blood cell counts) easy bruising or bleeding (due to low blood platelet counts) fatigue (due to low red blood cell counts),These side effects are usually shortterm and go away after treatment is finished. There are often ways to lessen these side effects. For example, there are drugs that can be given to help prevent or reduce nausea and vomiting. Some drugs such as cisplatin, vinorelbine, docetaxel, or paclitaxel can damage nerves. This can sometimes lead to symptoms (mainly in the hands and feet) such as pain, burning or tingling sensations, sensitivity to cold or heat, or weakness. (This is called peripheral neuropathy.) In most cases this goes away once treatment is stopped, but it may be long lasting in some people.,Lasting time,Thank Y