【正文】
36。)誘導,機械(jīxi232。)通氣,第四十二頁,共四十九頁。,1.6.3 Matching of Ventilation and Perfusion,Induction of anaesthesia does not affect the distribution of perfusion except that the increased intrathoracic pressure of mechanical ventilation may reduce cardiac output and increase or create the zone in the lung where alveolar pressure exceeds pulmonary arterial pressure, thus increasing dead space.,胸內壓,肺動脈壓,肺泡(f232。ip224。o)壓,第四十三頁,共四十九頁。,The distribution of ventilation is impaired during spontaneous respiration and worsened with mechanical ventilation when there is a reduction in the ventilation to the dependent parts of the lung.,自主(z236。zhǔ)呼吸,機械(jīxi232。)通氣,第四十四頁,共四十九頁。,1.6.4 Gas exchange and Carriage,Gas exchange is impaired during anaesthesia as outlined above and oxygen carriage may be impaired by the reduced cardiac output. By reducing the PaCO2 hyperventilation reduces oxygen delivery by shifting the oxyhaemoglobin dissociation curve to the left. The associated vasoconstriction further impairs tissue oxygenation.,第四十五頁,共四十九頁。,1.6.5 Increased Oxygen Consumption,Shivering commonly occurs in the postoperative period causing a marked increase in oxygen consumption. Cardiac output cannot always increase to meet the demand and mixed venous oxygen tension decreases.,混合(h249。nh233。)靜脈血氧分壓,術后期(h242。uqī),寒顫(h225。nzh224。n),第四十六頁,共四十九頁。,1.6.6 Second Gas Effect,Under normal circumstances only oxygen is taken up from the lungs and there is no net uptake of nitrogen. When a second gas which is absorbed rapidly, the uptake of that gas has the effect of 39。concentrating39。 the gases remaining in the alveoli. The effect on oxygen is of no clinical importance but the increase in concentration of volatile anaesthetic agents speeds the induction of anaesthesia.,第四十七頁,共四十九頁。,第四十八頁,共四十九頁。,內容(n232。ir243。ng)總結,祝同學們新年學習進步(j236。nb249。)。forced vital capacity(VC):用力肺活量。anatomical dead space:解剖無效腔。Haldane effect:Haldane效應。second gas effect:第二氣體效應。麻醉誘導,第四十九頁,共四十九