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thione level[J] . Environ Health Perspect,1995,103(suppl):8588. [11]李富君,孫貴范,戴國(guó)鈞,[J].中國(guó)地方病學(xué)雜志,1998,17(1):9. ?。?2]Smith AH, HopenhaynRich C, Warner M, et al. MT Rationale for selecting exfoliated bladder cell micronuclei as potential biomarkers for arsenic genotoxicity[J]. Toxicol Environ Health,1993, 40(23): 223234. ?。?3]Warner ML, Moore LE, Smith MT, et al. Increased micronuclei in exfoliated bladder cells lf individuals who chronically ingest arseniccontaminated water in Nevada[J]. Cancer Epidemiol Biomarkers Prev,1994,3(7):583590. [14]Liou SH, Gu TL, Chen CJ, et al. Hypersensitivity to mitomycin Cinduced sister chromatid exchange as a biomarker of past exposure to arsenic[J]. Cancer Epidemiol Biomarkers Prev, 1996,5(2): 103107. ?。?5]Liou SH, Lung JC, Chen YH, et al. Increased chromosometype chromosome aberration frequencies as biomarkers of cancer risk in a blackfoot endemic area[J]. Cancer Res,1999,59(7):14811484. [16]Hermesz E, Gazdag AP, Ali KS, et al. Differential regulation of the two metallothionein genes in mon carp[J]. Acta Biol Hung,2002,53(3):343350. ?。?7]Schuliga M, Chouchane S, Snow ET. Upregulation of glutathionerelated genes and enzyme activities in cultured human cells by sublethal concentrations of inorganic arsenic[J]. Toxicol Sci,2002,70(2):183192. ?。?8]Chiou HY, Hsueh YM, Hsieh LL, et al. Arsenic methylation capacity, body retention, and null genotypes of glutathione Stransferase M1 and T1 among current arsenicexposed residents in Taiwan[J]. Mutat Res,1997,386(3):197207. ?。?9]Ahsan H, Chen Y, Kibriya MG, et al. Susceptibility to arsenicinduced hyperkeratosis and oxidative stress genes myeloperoxidase and catalase[J]. Cancer Lett, 2003,201(1):5765. ?。?0]Yu L, Kalla K, Guthrie E, et al. Genetic variation in genes associated with arsenic metabolism: glutathione Stransferase omega 11 and purine nucleoside phosphorylase polymorphisms in European and indigenous Americans[J]. Environ Health Perspect, 2003,111(11):14211427.內(nèi)容總結(jié) (1)認(rèn)識(shí)地方性砷中毒