抗體的選擇和保存指南-資料下載頁
2025-08-23 00:55本頁面
【正文】 RelA/p65 are phosphorylated in response to several stimuli including phorbol ester, IL1 alpha and TNF alpha as mediated by IkB kinase and p38 MAPK. Serine 529 is located in a negatively charged region (amino acids 422540) that is phosphorylated in response to phorbol myristate acetate plus calcium ionophore activation. Phosphorylation of serines 529 and 536 is critical for RelA/p65 transcriptional activity. Activated NFkB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFkB has been associated with a number of inflammatory diseases while persistent inhibition of NFkB leads to inappropriate immune cell development or delayed cell growth.Alternative names for NFkB p105 / p50 antibody [E381] (ab32360)Database links The links below go to external sites and will open in a new browser windowEntrez Gene4790(Human)18033(Mouse)81736(Rat)GeneCardGC04P103880(Human)Omim164011(Human)SwissProtP19838(Human)P25799(Mouse)Q63369(Rat)Unigene431926(Human)Raised in RabbitClonality MonoclonalClone number E381Isotype IgGPurity Protein A purifiedStorage buffer Preservative: % Sodium AzideConstituents: 40% Glycerol, % BSA, Sodium chloride, 50mM Tris glycine. pH Material safety datasheets (MSDS) for this product:Form LiquidStorage instructions Shipped at 4176。C. Upon delivery aliquot and store at 20176。C. Avoid freeze / thaw cycles.
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鄂ICP備17016276號-1