【正文】
將該方法試驗性的用于輔助臨床診斷,并取得一定成效,在臨床癥狀不典型,PPD診斷不明確,涂片及培養(yǎng)均為陰性的疑似結核病患者中,輔以ELISPOT方法,可以幫助確診結核感染。參考文獻[1]侯世芳,許賢豪,劉廣志等,酶聯免疫斑點(ELISPOT)技術的應用. 中國神經免疫學和神經病學雜志,2002。10(9):200202.[2] Lalbani A. Spotting latent infection: the path to better tuberculosis 2003。58:916918[3] Philip C, Roger H, Annette F, et al. Largescale evaluation of enzymelinked immunospot assay and skin test for diagnosis of Mycobacterium tuberculosis infectection against a gradient of exposure in the Infect 。38:966973.[4]Liebeschuetz S, Bamber S, Ewer K, et al. Diagnosis of tuberculosis in South African children with a Tcellbased assay: a prospective cohort study. Lancet. 2004。364(9452):21962203.[5]Chapman AL, Munkanta M, Wilkinson KA, et al. Rapid detection of active and latent tuberculosis infection in HIVpositive individuals by enumeration of Mycobaterium tuberculosisspecific T . 2002,16:22852293.