【正文】
the Bcell receptor and Tcell receptor, respectively. ( T )4. Antigenpresenting cells express both class I and class II MHC molecules on their membranes. ( T )5. Babies can acquire IgEmediated allergies by passive transfer of maternal antibody. ( F )6. Both CTLs and NK cells release perforin after interacting with target cells. ( T )7. Target cell lysis and destruction can be achieved by perforin released from antigenspecific cytotoxic Tcells ( T )8. The immune response is mediated via the humoral and/or cellular arms of the immune system ( T )9. Immediate type hypersensitivity is mediated by IgM. ( F )10. All cytokinebinding receptors cintain two or three subunits. ( T )Ⅲ Answer the following questions in brief (104points =40 )1. Name the three types of professional APCs, and give one example of nonprofessional APCs. B M DC endothelial cell2. Summarize the four major functions of plement system ①lysis of cells, bacteria and viruses ②opsonization to enhance phagocytosis ③clearance of immune plexes ④stimulation of inflammation3. List the classical Class I and Class II gene loci for humans 4. What dose MHC restriction mean?HLAA,B,C HLADPDRDQ5. To activate T cells, two molecules must be recognized on the antigenpresenting cells, what are they? PeptideMHC6. Compare the primary and secondary responses from the following points of view: (a) time for antibody to appear (b) quantity of antibody produced (c) class of antibody produced (d) duration of antibody production.7. Compare Class I and Class II MHC proteins from the following points of view: (a) types of cells on which they are located (b) role in antigen recognition by CD4+ and CD8+ T cells. 8. Helper T cells can be divided into two subsets based on their lymphokine secretion profile. Explain. 9. What are the main functions of macrophages?10. Please draw a schematic diagram of a typical IgG molecule and label each part of the chains.