基因芯片技術(shù)在耐藥檢測(cè)中的研究概況doc-資料下載頁(yè)
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【正文】 另外基因芯片在農(nóng)業(yè)、食品監(jiān)督、環(huán)境保護(hù)、司法鑒定等方面都將作出重大貢獻(xiàn)。基因芯片的飛速發(fā)展引起世界各國(guó)的廣泛關(guān)注和重視。鑒于基因芯片的巨大潛力和誘人的前景，基因芯片已成為各國(guó)學(xué)術(shù)界和工業(yè)界研究和開發(fā)的熱點(diǎn)。隨著現(xiàn)代微加工技術(shù)的進(jìn)步和納米技術(shù)的發(fā)展，生物芯片在容納更多信息的同時(shí)日趨微型化和價(jià)格普及化，其在疾病診斷和藥物篩選等方面的應(yīng)用前景將更加廣闊?；蛐酒纳钊胙芯亢蛷V泛應(yīng)用，將對(duì)21世紀(jì)人類生活和健康產(chǎn)生極其深遠(yuǎn)的影響。參考文獻(xiàn)：[1]Ramsay :stateoftheart[J].Nat Biotechnol,1998,16(1):4044.[2]梁國(guó)棟,[M].北京:．[3]Hacia JG,Brody LC,Chee of heterozygous mutations in BBCAI using high density oligonucleotide arrays and twocolour lurescence aoalysis[J].Nature genetics ,21:4247.[4]顏?zhàn)臃f,王海林,[M]. 北京:科學(xué)出版社,1998:186189.[5]Chee M,Yang R,Hubbell E,et genetic information with high density DNA aray[J]. Science,1998,280:10461048.[6]Winzeler EA,Richards DR，Conway AR,et variation scanning ofthe yeast genae[J].Science,1998,23(1):7476.[7]嚴(yán)杰,羅海波,[M].北京:人民衛(wèi)生出版社,1997,10:44.[8]王曉利,[J].生物技術(shù),2002,12(1):20.[9]Gonzales EG,Olazzran MG,Menchaca RT,et of drug susceptibility of Mycobacterium tubemosis through mycolic acid alysis[J].J Clin Microbiol，1997,35(5):12871289．[10]Troeseh A,Nguyen H,Miyada CG,et identification and rifampin resistance testing with highdensityDNA prob arrays[J].J Cain Microbiol,1999,37(1):4955．[11]Chee M,Yang R,Hubbell E,et genetic informarionwith highdensity DNA arrays[J].Science,1996,274(5287):610614．[12]張萬(wàn)江,鮑 朗,王曉櫻,張會(huì)東,謝勇恩,陳 瑋, Chinese Journal of Pathophysiology 2003,19(6):762764.[13]劉誠(chéng)明,[J].現(xiàn)代腫瘤醫(yī)學(xué),2003,11(5):390.[14]陳信義,李峨,侯麗,[J].中國(guó)中醫(yī)藥信息雜志,2004,11(10):922—923.[15]李峨,[J].中國(guó)中醫(yī)藥信息雜志,2004,11(2):103105.．[16]侯麗,劉雪強(qiáng),陳信義,張開泰,王玉芝, Journa1 Of Information on TCM :3436.[17]Rusiniak ME,Yu M，Ross DT,et ofB94 as a retinoic acid target gene in acute promyelocytic leukemia[J].Cancer Res,2000,60:18241829．[18]Rozovskaia T,Feinstein E,Mor O,er of Meisl andHoxA9 in acute lymphocytic with the t(4:11)abnormality[J].Oncogene,2001,20:874878.[19]Kapp U,Yeh WC,Patterson B,et is secretedby and stimulates the growth of Hodgkin and ReedSternberg cells[J].Exp Med,1999,189:19391945.[20]Hofmann WK,de Vos S,Tsukasaki K,et apoptosis pathways in mantle cell lymphoma detected by oligonucleotide microarray[J].Blood,2001,98:787794．[21]Bosch F,Jares P,Campo E,et liferative disorders:a highly specific marker of mantle cell lymphoma[J]. Blood,1994,84:27262732．[22]顧春紅,陳芳源,滕曄,[J].上海醫(yī)學(xué),2001,24(5):263265. 7 /
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