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【正文】 ion of thermoresponsive aminereactive polymers prepared by RAFT, Polymer Chemistry 2022, 2, 323327 Lysine ? Challenge for protein polymer conjugate : amixing ratio, bprotein loading capacity, cstudy of uptake efficiency with different inhibitors for different cellular entry mechanism for maximum delivery efficiency. ? Cost amp。 storage ? Protein therapeutics: a summary and pharmacological classification, enjamin Leader, Quentin J. Baca amp。 David E. Golan Nature Reviews Drug Discovery 7, 2139 (January 2022) | doi: ? Intracellular Protein Delivery Systems Formed by Noncovalent Bonding Interactions between Amphipathic Peptide Carriers and Protein Cargos, by, Seong Loong Lo, Shu Wang* Macromol. Rapid Commun. 2022, 31, 1134–1141 ? What are the advantages of Protein therapeutics over the small molecule drugs? ? What are the different types of protein therapeutics? Give examples. ? What are rebinant proteins? What are their benefits over nonrebinant proteins? ? Explain with example the strategy of development of protein therapeutics for targeted delivery. What features of proteins are important in this context?
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