【正文】 ar the cost of printing them, except in the case of invited papers. The charges for these figures are $1500 for the first color figure or part of a figure, and $500 for each additional color figure or part of a figure. Authors will be billed for color publication costs unless they request that their figures be printed in black and white.該雜志一般為2個(gè)審稿人，審稿過(guò)程也較嚴(yán)格，都是本領(lǐng)域的大牛。后來(lái)我還有幸在一次會(huì)議上認(rèn)識(shí)到一個(gè)當(dāng)年的審稿人，但不知道是1還是2，呵呵！一般總是先鼓勵(lì)一段話(huà)，不寫(xiě)了。下面問(wèn)題就來(lái)了，共12個(gè)，有些很好回答，一句話(huà)就可以解釋清楚，有些就比較麻煩。還是舉例說(shuō)明把1）實(shí)驗(yàn)的有效性和深度（at least for a few substances of major importancedetection limits, cutoff values and specificity should have beenstudied. Also the description of the assay principle is not quiteclear）沒(méi)辦法，只有一條路，補(bǔ)充相關(guān)實(shí)驗(yàn)，然后再投。2）語(yǔ)言問(wèn)題（The English text would have to be substantially improved）雖然這是一個(gè)美國(guó)雜志，但對(duì)語(yǔ)言的要求一點(diǎn)都不弱，投之前還是忽略了，沒(méi)辦法，慢慢修改。3）核心的技術(shù)問(wèn)題（A cutoff value is given for MOL but the dimension is missing. In the discussion various anecdotic reports are given for which no data are presented under results.） 重新驗(yàn)證討論。 本來(lái)認(rèn)為很快就可以接受了，沒(méi)想到卻又等了一個(gè)半月（中間發(fā)過(guò)一次信件詢(xún)問(wèn)）才收到回信。原來(lái)除了上次2個(gè)評(píng)委，這次又增加了一個(gè)獨(dú)立審稿人。原文如下：Your revised manuscript. has been examined by the original two reviewers, plus a remended third reviewer with special expertise in this area. Please visitto retrieve their ments. The three reviewers find merit in the work, but have numerous constructive suggestions（別害怕，其實(shí)就是幾個(gè)小問(wèn)題）. Please consider these suggestions carefully and prepare an improved version that addresses these concerns. I have also noted that there are several color figures included in the paper, which seem to be useful only in color. Please be aware that (should your paper be accepted for publication) authors are expected to pay the costs for publication of color figures. The charge for the first color figure is $1500。 subsequent figures, or parts of figures, are $500 each. Of course, if you wish to submit alternate figures in black and white (or grayscale), you may do so.Sincerely,Dr. xxxAssociate Editor. You will find your revised manuscript. can be uploaded in your Submit a Revision queue at.A checklist of requirements for submission can be found atWhen uploading the revised version, please be sure to include in the Response to Reviews field a pointbypoint list of all changes made, or your rebuttal, in response to each of the reviewer suggestions. Also, please submit copyright releases for all authors. Our Authors39。 Assurances and Assignment of Copyright form. can be downloaded fromPlease note that all authors must sign both sections of the form. Send the pleted form. to us by FAX (4349797599).. For figures, please submit .tif files that have a minimum resolution of 600 DPI。 the width and height of the Pixels should be about 4200 x 4200. Alternatively, you may use PowerPoint for figures, but each .ppt file may contain only one slide and fonts must be embedded.總之一句話(huà)，還是需要再次修改。又等了接近1個(gè)月時(shí)間，幸虧不是學(xué)生趕畢業(yè)，最終被接收了。Thank you for your revised manuscript. It is acceptable and will be processed for publication. Please note that I edited the paper to remove all text related to Figure 6. The structures of the drugs are available to anyone who wants to look them up. Thus this figure will not be in the proofs that you receive.如果proof快的話(huà)，這個(gè)雜志一般會(huì)安排在23個(gè)月后發(fā)表。If page proofs are returned promptly, your paper is scheduled to appear in the Oct in press are posted online 26 weeks before the issue date. Issues are scheduled to be mailed to subscribers and appear on the Internet before the first day of the issue month. The electronic version () is published at Stanford University39。s HighWire Press, where your article will be linked electronically to and from PubMed and directly to and from over 340 other journals that are online at to publication we require copyright releases signed by all authors. Our Authors Assurances and Assignment of Copyright form. can be downloaded fromPlease note that all authors must sign both sections of the form. (a signature on the lower section means that all conflicts of interest have been disclosed even if there are none).Thank you for this contribution.Sincerely,Dr. xxAssociate Editor我們的回復(fù)Dear Dr.,Thank you very much for giving me an opportunity to revise the above manuscript.According to the reviewers39。 ments, we have revised the manuscript to provided our explanation.Furthermore, we revised the paper according to your suggestion.1) The length of abstract is 194 words, and the word of the main text is 2550.2) The layout and format guidelines have been followed.3) The changes to the paper have been highlighted underlined as well as including detailed responses to the reviewers ments.I hope you are satisfied with the revised version, however, if there is more question, we are willing to revise it again.Thank you.e from