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armacological Effects (1) AntiInflammatory Effect (2) Immunosuppressive Effect (3) AntiShock Effect (4) To lower body T (5) To stimulate bone marrow red cell production (6) To raise BP Clinical Pharmacology of Glucocorticoids 1. Adrenocortical Insufficiency (1) Chronic ( Addison’s Disease) Infection Hypotension and Low blood suger level Shock or death When in stress, what about the dose? (2) Acute (Addison’s Disease) Large dose, IV, and slowly to Maintenance Dose 2. Severe Infection 3. Autoimmune disease 4. Shock 5. Aplastic anemia 6. Local use 7. Replacement therapy Case 5 Iron Deficiency Anemia Secondary to Idiopathic Thrombocytopenic Purpura( ITP) A patient, 45 years old, from Fuxin, Liaoning, was diagnosed to be iron deficiency anemia secondary to Idiopathic Thrombocytopenic Purpura( ITP) and had been treated using medicines. Because of money problem. She stopped treatment by herself when recovered. Two tears later, today, her anemia with ITP took place again. Symptoms: chest pain, mouth blood bubble, gingival bleeding, fatigue, difficult walking. What medicines should be prescribed for the patient? What about their Ads and contraindications? How to explain the symtoms? Prednison( 12Tabs/day) Ferrous Fumarate 血康 Case 6 Leukemia Another patient, female, 52, got leukemia, and treated using medicines and recovered. Someday, the patient came back to the hospital to check again, and told her doctor: When using those medicines, my hair was lost, and after stop the use of the drug, my hair came back again, but all hair all over my body changed into curls. The doctor told her: everything is okay, I had met with a patient with blood type change after treatment but never seen such a case before. What agents might be used for the treatment of the patient? Why those agents can change hair or blood type? Interferon Hydroxycarbamide Ubenimex Capsules Imatinib Mesylate Capsules