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hwann cells cover the axon and its terminal bag. For a long time it was believed that only the young brain can undergo such structural changes. However, recent findings have shown that the adult brain can also grow, reanize and form new connection between neurons. Thus, the research on neuroplasticity points to the brain as a growing an that responds structurally not only to the demands of the external environment, but also to internally generated states, including aspects of consciousness. Neuronal plasticity the ability of neurons in the brain to change in response to experience, has been one of the most exciting discoveries in neuroscience. Neural stem cell(NSC) Step One Neural Stem Cells Neural stem cells (NSC) are cells that can mature into any type of cell and can continually renew themselves. Step Two Progenitor Cells Progenitor cells do not themselves perform active neurological functions but are “reserve” cells that bee activated when mature nerve tissue is damaged. The progenitor cells can develop into mature active cells in order to repair or replace the damaged tissue. Progenitor cells include: GRP: GlialRestricted Precursors NRP: Neuron Restricted Precursors O2A/OPC: OligodendrocyteType2 Astrocytes Step Three Mature Nerve Cells Astrocytes Neurons are the primary nerve cells in the nervous system that process and transmit information via electrical signals. Oligodendrocytes Alzheimer39。s disease (AD): also known simply as Alzheimer39。s, is a neurodegenerative disease characterized by progressive cognitive deterioration together with declining activities of daily living and neuropsychiatric symptoms or behavioral changes. The most striking early symptom is loss of shortterm memory (amnesia), which usually manifests as minor fetfulness that bees steadily more pronounced with illness progression, with relative preservation of older memories. As the disorder progresses, cognitive (intellectual) impairment extends to the domains of language (aphasia), skilled movements (apraxia), recognition (agnosia), and functions such as decisionmaking and planning get impaired. President Reagan Degeneration and Regeneration ? If axon cut, distal part degenerates ? In PNS distal part will regenerate ? If cut too close to cell body, cell body may die ? CNS axons do not regenerate well Objectives for Nervous Tissues 1. to classify the neurons by characteristics of form and function. 2. to describe the form and function of the structures found within typical nerve cell bodies. 3. to describe the form and function of typical nerve cell processes (., axons and dendrites). 4. to define and/or describe the form and function of Synapses and neuroglial cells. 5. to pare and contrast myelination of peripheral versus central nervous tissues. 6. to describe the anization and structure of peripheral nerves.