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- + + + + 00. 511. 520 0 1 2. 5 5Cytosol/nuclear NFκB p65 fold Fucoidan( mg/ml) - + + + + Cytosol Nuclear βactin Fig. Effect of Fucoidan on the secretion of NO by LPSstimulated cells (n=3). Fig. Effect of Fcoidan on the protein expression of NFκB p65 by LPSstimulated cells (n=3). * * * * * AA induce Animal Model ~ Induction of earskin inflammation 00 . 10 . 20 . 30 . 40 . 50 m i n 4 0 m i n 3 h r 6 h r 2 4 h r(%)c o n t ro ll o w00 . 10 . 20 . 30 . 40 . 50 m i n 4 0 m i n 3 h r 6 h r 2 4 h r(%)c o n t ro lmed00 . 10 . 20 . 30 . 40 . 50 m i n 4 0 m i n 3 h r 6 h r 2 4 h r(%)c o n t ro lh i g h* * * Fig. The effect of Fucoidan on the ear thickness of ear inflammation. 未 誘 發(fā) Low Med. High 40 min 6 hr 24 hr Fig. The effect of Fucoidan on RBC fraction of tissue volume of ear inflammation. Control Positive control Low dose Med. dose High dose Fig. Pictures of the effect of Fucoidan on neutrophil satin of ear inflammation. 行政院農(nóng)委會(huì)水產(chǎn)試驗(yàn)所 水產(chǎn)加工組 THANKS FOR YOUR ATTENTION