ropofol(diprivan)andit39sadverseeffectinanesthesia：丙泊酚異丙酚和它的不良影響在麻醉-資料下載頁(yè)
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【正文】 hmias, metabolic acidosis, cardiac failure, and death related to propofol use can occur in adults as well as in children Metabolic acidosis and fatal myocardial failure after propofol infusion in children: five case reports BMJ 1992。 305:613–616 ?increasing metabolic acidosis was associated with bradyarrhythmia and progressive myocardial failure, which did not respond to resuscitative measures ?CONCLUSION— ? Although the exact cause of death in these children could not be defined, propofol may have been a contributing factor. Morphologic changes in the upper airway of children during awakening from propofol administration. Anesthesiology Volume 96 ? Number 3 ? March 2022 Copyright 169。 2022 American Society of Anesthesiologists, Inc. ? CONCLUSIONS: ? The dimensions of the upper airways of children change shape significantly on awakening from propofol sedation. ? When sedated, the upper airway is oblong shaped, with the AP diameter larger than the transverse diameter. ? On awakening, the shape of the upper airway in most children changed such that the transverse diameter was larger. Crosssectional areas between sedated and awakening states were unchanged. ? These changes may reflect the differential effects of propofol on upper airway musculature during awakening A parison of ketamine and lidocaine spray with propofol for the insertion of laryngeal mask airway in children: a doubleblinded randomized trial. Anesth Analg 01DEC2022。 95(6): 15869 ?Ketamine and lidocaine spray appear to be appropriate for laryngeal mask airway (LMA) insertion in children. ?apnea and airway obstruction, the two most serious and frequent plications of propofol, can be avoided during LMA insertion. Thanks for your attention!
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