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0 . 2 50 . 0 00 . 2 5p 0 . 0 5% c h a n g e o f p a i n t h r e s h o ld ( r a d i a n th e a t w i t h d r a w a l)Correlation Coefficient44 Brain areas involved in AA: fMRI studies in humans Negative correlation 42 0 25 50 75 100 1250 .0 00 .2 50 .5 00 .7 51 .0 0r 2 = 0 .8 8 7 9p = 0 .0 0 0 1c h a n g e o f p a in t h r e s h o ld ( % )Correlation CoefficientR M I0 25 50 75 100 1250 .0 00 .2 50 .5 00 .7 50 . 7 81 10 . 0 01 6r 2 =p =c h a n g e o f p a in t h r e s h o ld ( % )Correlation CoefficientR S M A0 25 50 75 100 1250 .0 00 .2 50 .5 00 .7 50 . 6 0 5 40 . 0 1 3 5r 2 =p =c h a n g e o f p a in t h r e s h o ld ( % )Correlation CoefficientR S I I0 25 50 75 100 1250 .0 00 .2 50 .5 00 .7 5r 2 = 0 .7 6 6 50 . 0 02 0p =c h a n g e o f p a in t h r e s h o ld ( % )Correlation CoefficientL S I I0 25 50 75 100 1250 .0 00 .2 50 .5 00 .7 5 0 . 6 69 80 . 0 07 0r 2 =p =c h a n g e o f p a in t h r e s h o ld ( % )Correlation CoefficientL I n s0 25 50 75 100 1250 .0 00 .2 50 .5 00 .7 5r 2 = 0 .8 1 5 1p = 0 . 0 00 9c h a n g e o f p a in t h r e s h o ld ( % )Correlation CoefficientR B A 2 40 25 50 75 100 1250 . 0 00 . 2 5. 5 00 . 7 50 . 8 57 30 . 0 01 0r 2 =p =c h a n g e o f p a in t h r e s h o ld ( % )Correlation CoefficientR T h0 25 50 75 100 1250 .0 00 .2 50 .5 00 .7 5r 2 = 0 .8 2 5 0p = 0 . 0 00 7c h a n g e o f p a in t h r e s h o ld ( % )Correlation CoefficientL S T G0 25 50 75 100 125 0 .7 5 0 .5 0 0 .2 50 .0 00 .2 50 . 6 44 70 . 0 16 4r 2 =p =c h a n g e o f p a in t h r e s h o ld ( % )Correlation CoefficientR H i0 25 50 75 100 125 0 .7 5 0 .5 0 0 .2 50 .0 0r 2 = 0 .6 6 9 3p = 0 . 0 07 0c h a n g e f p a in t h r e s h o ld ( % )Correlation CoefficientL H i0 25 50 75 100 1250 .0 00 .2 50 .5 00 .7 50 . 2 87 00 . 1 37 1r 2 =p=c h a n g e o f p a in t h r e s h o ld ( % )Correlation CoefficientR S I0 25 50 75 100 1250 .0 00 .2 50 .5 00 .7 5 0 . 1 64 10 . 2 79 5r 2 =p =R I n sc h a n g e o f p a in t h r e s h o ld ( % )Correlation CoefficientRight Primary Motor Area Right Supplementary Motor Area Left Secondary Somatosensory Area Left Insula Right Secondary Somatosensory Area Left Superior Temporal Gyrus Right Thalamus Right Anterior Cingulate Cortex Right Hippocampus Right Hippocampus Right Primary Somatosensory Area Right Insula Effects of 2 Hz EA on the brain fMRI Summary Brain Areas 2 Hz 100 Hz RSensory II + + LSensory II + + RBroadman Area 24 + + RThalamus + + LInsular + + RPrimary Motor Area + RSupplementory MA + LSuperior Temporal Gyrus + RBroadman Area 40 + LBroadman Area 24 + LNucleus Accumbens + PONS + RHippocampus LHippocampus RAmygdala 肥 胖 癥 能量代謝失衡 對(duì)美食的渴求 藥物成癮 身體依賴:戒斷癥狀 精神依賴:心癮 痛與鎮(zhèn)痛 感知功能 情緒反應(yīng) 7 25 57 86 100 0 10 20 30 40 50 60 70 80 90 100 1990 1993 1997 2022 2022 Heroin addicts in China (ten thousand) 80% 85% heroin addicts Heroin addiction: can acupuncture help? 針刺是否能戒除 海洛因成癮? Han’s Acupoint Nerve Stimulator (HANS) 韓 氏 穴 位 神 經(jīng) 刺 激 儀