抗原的加工與遞呈(1)-資料下載頁
2025-05-15 05:50本頁面
【正文】 s are induced by IFN? and replace constitutive ponents to confer proteolytic properties. LMP2 amp。 7 encoded in the MHC Proteasome cleaves proteins after hydrophobic and basic amino acids and releases peptides into the cytoplasm Cytoplasmic cellular proteins, including nonself proteins are degraded continuously by a multicatalytic protease of 28 subunits Crystal Structure Of The 20s Proteasome From Yeast View End on Endoplasmic reticulum Peptide Peptide HSV protein blocks transport of viral peptides into ER Sent to lysosomes for degradation Evasion of immunity by interference with endogenous antigen processing （三）非經(jīng)典遞呈途徑 交叉遞呈 ? MHCI類分子也能遞呈外源性抗原，MHCII類分子也能遞呈內(nèi)源性抗原。 ? 不是抗原遞呈的主要方式。 四、抗原加工遞呈的意義 ? 實(shí)現(xiàn)免疫系統(tǒng)對(duì)非己抗原的免疫監(jiān)視作用 ? 免疫調(diào)節(jié)作用 小 結(jié) ? 基本概念： APC ? APC的種類 ? 內(nèi)外性抗原加工遞呈的過程 ? 生理意義
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