proteinkinasecanditsinvolvementinpathophysiologicdisorders-資料下載頁
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【導(dǎo)讀】Involvementin. JunfaLi,.Departmentof. Neurobiology. CapitalMedical. University. E-mail:. 4.PKC&Alzheimer’sdisease. 6.PKC&Pain. 7.PKC&Cardioprotection. 8.PKC&Cancer. E-mail:. Acyclicnucleotide-independent,proteolytically. 1979;91:1218–1224). E-mail:. PKCm,nPKD1,PKD3. E-mail:. E-mail:. E-mail:. Biochem.J.20xx;370:361–371. E-mail:. E-mail:. Biochem.J.20xx;370:361–371.E-mail:. E-mail:. protein.RACK1containsseven. equivalentWD40. domains,thisdrawing. depictsRACK1. conitantlybinding. enzymes(1-7),eachona. E-mail:. Oncogene20xx;20:6339-6347. signalingenzymes. E-mail:. Oncogene20xx;20:6339-6347. PKC-bindingsiteonRACK.E-mail:. Oncogene20xx;20:6339-6347. E-mail:. E-mail:. E-mail:. E-mail:. PKC&Cerebral. Ischemia/. ReperfusionInjury. Disord
【正文】 h 20xx。 55: 578–589 ODN: antisense oligodeoxynucleotide。 PAG: periaqueductal gray。 RVM: rostral ventromedial medulla。 NRM: nucleus raphe magnus. Email: PKC amp。 Cardioprotection PKC Involved in Pathophysiologic Disorders Email: ? Proposed cardioprotective targets of nPKC? Pharmacological Research 20xx。 55: 523–536 Email: ?Proposed mechanism for nPKC?mediated regulation of mitochondrial function leading to IR injury Pharmacological Research 20xx。 55: 523–536 Email: PKC amp。 Cancer PKC Involved in Pathophysiologic Disorders Email: ? Schematic of placement of PKC isoforms in intracellular signaling pathways Clin Cancer Res 20xx。12: 53365345 Email: ?Schematics illustrating the factors involved in intracellular signaling pathways upstream of PKC? Clin Cancer Res 20xx。12: 53365345 Email: ?Schematics illustrating the factors involved in intracellular signaling pathways downstream of PKC? Clin Cancer Res 20xx。12: 53365345 Email: ?Schematics illustrating the factors involved in intracellular signaling pathways upstream of PKC? Clin Cancer Res 20xx。12: 53365345 Email: ?Schematics illustrating the factors involved in intracellular signaling pathways downstream of PKC? Clin Cancer Res 20xx。12: 53365345 Email: ?The PKC family is important in normal keratinocyte (角質(zhì)化細(xì)胞 ) biology and in skin diseases, especially skin cancer. (Int JBiochem Cell Biol 20xx。36:11416.) ?PKC activity is higher in actively proliferating colonic epithelial cells than in their quiescent counterparts. (J Biol Chem 20xx。279:94008) ?PKC? and PKC? promote apoptosis in androgen (雄激素 ) dependent prostate cancer cells. (Curr DrugTargets 20xx。5:43143) ?aPKC? is highly expressed in human non–small cell lung carcinoma (NSCLC) lines, whereas the closely related PKC isozyme, aPKC?, is undetectable in these cells. (J Biol Chem 20xx。280:3 110915) Email: ? Schematic representation of major oncogenic PKC signaling pathways Pharmacological Research 20xx。 55: 487–497 Email: PKC amp。 diabetic retinopathy PKC Involved in Pathophysiologic Disorders (動脈瘤 ) (視網(wǎng)膜病變 ) Email: ? PKC activation is likely to play a key role in diabetic microvascular plications (并發(fā)癥 ), particularly changes in vascular permeability and ischaemia in the retina. ? A new potential therapeutic agent, the PKC? inhibitor ruboxistaurin, has been studied in animal and human clinical trials in diabetic microvascular diseases, particularly diabetic retinopathy.(Best Practice amp。 Research 20xx。 21: 573586) Email: ? Activation of PKC via glycolysis (糖酵解 ) Best Practice amp。 Research 20xx。 21: 573586 (醛糖還原酶 ) (山梨糖醇 ) (果糖 ) (多元醇途徑 ) (丙酮酸 ) Email: ? PKC action in vascular tissues Best Practice amp。 Research 20xx。 21: 573586 Email: Pharmacological Research 20xx。 55: 498–510 ? Mechanism of DAGPKC activation Email: ?Physiological effects and cellular mechanisms of DAGPKC activation induced hyperglycemia Pharmacological Research 20xx。 55: 498–510 (高血糖癥 ) (氨基胍 ) (糖化 ) Email:
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