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colleagues in the early 1960s. Austrian biochemist 8電子傳遞與氧化磷酸化 Mitochondrial ATP synthase plex John E. Walker 8電子傳遞與氧化磷酸化 Mitochondrial ATP synthase plex 8電子傳遞與氧化磷酸化 Paul D. Boyer John E. Walker Jens C. Skou 1/4 of the prize 1/4 of the prize 1/2 of the prize University of California Los Angeles, CA, USA MRC Laboratory of Molecular Biology Cambridge, United Kingdom Aarhus University Aarhus, Denmark enzymatic mechanism underlying the synthesis of ATP Na+, K+ ATPase The Nobel Prize in Chemistry 1997 8電子傳遞與氧化磷酸化 ?“O”態(tài)(開放態(tài)):不能與底物和產(chǎn)物結合 ?“ L”態(tài)(松散態(tài)):與底物的結合較松弛,對底物沒有催化能力 ?“ T”態(tài)(緊密態(tài)):與底物結合緊密,并有催化活性 8電子傳遞與氧化磷酸化