篇第九章白血病ppt課件(編輯修改稿)
2025-02-01 15:39 本頁面
【文章內(nèi)容簡介】 Blood test findings Anemia is a constant red cells or immature red blood cell may be present. Thrombocytopenia is nearly always present at the time of total leukocyte counts can be high, normal or low. Immature hematopoietic cells are almost present in the blood Marrow findings Normal bone marrow AML marrow Cytogeic findings Diagnosis amp。 Classification Other newly developed methods Morphology : the bone marrow cells are evaluated according to their size,shape, and content of granules and then they are classified with respected to maturity Cytochemistry staining: identification of the chemical ponents of cells is conducted to distinguish different types of leukemia. Cytochemistry often use special colored dyes Acute leukemia AML ALL M0: undifferentiated AML M1: Myeloblastic leukemia (without maturation) M2: Myeloblastic leukemia (with maturation) M3: promyelocytic leukemia M4: Myelomonocytic leukemia M5: Monocytic leukemia M6: Erythroleukemia M7: Megkaryoblastic leukemia L1: Mature appearing lymphoblasts L2: Immature and variously shaped lymphoblasts L3: Lymphoblasts are large and uniform P142 (CD tables) A lot of CD provides clues for the diagnosis Flow Cytometry Immunohistochemistry Immnuophenotyping panel used in St. Jude Children’s research hospital . CD13 CD33 CD19 CytoCD79a CD7 CytoCD3 AML BALL TALL By using this method of analysis, one can make a firm diagnosis in 99% of cases 免疫表型分型方案 T 細(xì)
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