【正文】
teban 1999 versus 120m with PSV of up to 7cm, Perren 2021 1/3 of failures occur after 30m Refining Years Author Year Main findings/ments V Ely 1999 SBTs may be safely performed khamiees 2021 in patients who are Epstein 2021 hemodynamically stable and have modest oxygen requirements VI Kollef 1998 Nurse driven sedation protocols, Brook 1999 bolus dosing of sedatives, and daily Kress 2021 cessation of sedatives can each shorten a patient?s length of stay on the ventilator Clinical Guideline VIII MacIntyre 2021 Evidencedbased guidelines for Jacobi 2021 ventilator weaning and sedation in the ICU ? ?Weaning ? 的名詞定義 1. 歷史傳統(tǒng)的定義 :有準(zhǔn)備的、緩慢的撤離通氣支持的過程 脫機(jī) 2. 現(xiàn)代危重病醫(yī)學(xué)的定義 : 一旦確定病人有自主呼吸能力 ,應(yīng)盡早的、安全的、迅速的撤離機(jī)械通氣 脫機(jī)指標(biāo)的作用 ? ? 過去的 30年 66項脫機(jī)指標(biāo)在臨床使用 ,也有不少的 RCT研究 ? 由于醫(yī)生的問題不能有效撤離機(jī)械通氣 ,使通氣時間增加 2/3 Esteban(1994) Chest 106:11881193 Esteban(2021) JAMA 287:345355 ? 我們現(xiàn)有的指標(biāo)確定脫機(jī)成功陽性率 50%,陰性率 67% Stroetz (1995) Am J Respir Crit Care Med 152:10341040 Predictive values for individual weaning parameters Predictor Likelihood ratio Sensitivity% Specificity% MV(1012liters) 50 40 RR 97