bridion174-sugammadex-免費閱讀
【正文】 Sugammadex Summary ? Bridion?, sugammadex, is firstinclass cyclodextrin that directly reverses neuromuscular blockade ? It is indicated for the reversal of neuromuscular blockade for rocuronium and vecuronium for patients undergoing surgical procedures only ? Dosed: 24 mg/kg IV bolus based on total body weight OR 16 mg/kg IV bolus reserved for emergent reversal ? Offers faster reversal times pared to neostigmine ? All women of child bearing age should be counseled on using backup contraception for 7 days postop ? It is not cost prohibitive, but is more expensive than neostigmine Bridion174。 Sugammadex Dosing Information ? Dosing: ? 24 mg/kg IV bolus based on actual body weight depending on blockade status ? Immediate Reversal: 16 mg/kg IV bolus based on actual body weight ? This dose has only been studied for rocuronium reversal Bridion174。 Sugammadex Clinical Application ? Pregnancy: ? No available human data ? In animal studies, fetal birthweight was reduced when 8x human dose was administered ? Lactation: ? Unknown excretion in human breast milk ? Present in animal milk Bridion174。 S
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