【正文】 } [1%] ? Bradycardia (1%) {5%} [1%] ? Hypotension (4%) {13%} [4%] ? Anaphylaxis (0%) {1%} [0%] Bridion174。g/kg). Eur J Anaesthesiol 2020。 Sugammadex Drug Facts ? Mechanism of Action ? Cyclodextrin that forms a 1:1 plex with rocuronium and vecuronium ? This reduces the amount of free NMB agent in plasma ? In turn, the concentration gradient favors movement of NMB agent away from the neuromuscular junction Bridion174。 Sugammadex Bridion174。18:99. ? Included: Adult patients scheduled for surgery under general anesthesia in the supine position ? 18 years old ? ASA class 1 to 3 ? Primary oute: Recovery time after reversal agent administration ? measured as train of four ratio (T4/T1) of Blobner M, et al. Eur J Anaesthesiol. 2020。18:99. ? Sugammadex achieved significantly faster recovery of T4/T1 ratio to pared with neostigmine after neuromuscular block with rocuronium ? Outliers and variability of recovery times were significantly lower following reversal with sugammadex Blobner M, et al. Eur J Anaesthesiol. 2020。 [package insert]. Bridion174。 Sugammadex Clinical Application ? P