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bridion174-sugammadex-文庫吧

2025-08-27 09:05 本頁面


【正文】 human data ? In animal studies, fetal birthweight was reduced when 8x human dose was administered ? Lactation: ? Unknown excretion in human breast milk ? Present in animal milk Bridion174。 [package insert]. Bridion174。 Sugammadex Drug Facts ? Mechanism of Action ? Cyclodextrin that forms a 1:1 plex with rocuronium and vecuronium ? This reduces the amount of free NMB agent in plasma ? In turn, the concentration gradient favors movement of NMB agent away from the neuromuscular junction Bridion174。 [package insert]. Bridion174。 Sugammadex Drug Facts ? Drug Interactions: ? Hormonal contraceptives: must remend additional, nonhormonal method of contraception for next 7 days ? Toremifene: recovery can be delayed Bridion174。 [package insert]. Bridion174。 Sugammadex Adverse Effects ? Side effects are dosedependent ? Common (24 mg/kg) {16 mg/kg} [placebo]: ? Nausea (23%) {26%} [23%] ? Vomiting (11%) {15%} [10%] ? Serious (24 mg/kg) {16 mg/kg} [placebo]: ? Prolonged QT interval (1%) {6%} [1%] ? Bradycardia (1%) {5%} [1%] ? Hypotension (4%) {13%} [4%] ? Anaphylaxis (0%) {1%} [0%] Bridion17
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